Evidence map›Paper›PMID 33859639›Full record

ArticleFrontiers in immunology2021

The Outcome of Neutrophil-T Cell Contact Differs Depending on Activation Status of Both Cell Types.

Danielle Minns, Katie J Smith, Gareth Hardisty, Adriano G Rossi, Emily Gwyer Findlay

Abstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Neutrophils in cancer.Nature reviews. Cancer · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. The roles of neutrophils in cardiovascular diseases.Frontiers in cardiovascular medicine · 2025
    Review
  12. Activated neutrophils: A next generation cellular immunotherapy.Bioengineering & translational medicine · 2025
    Review
  13. Article
  14. CD4Acta biomaterialia · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danielle MinnsCentre for Inflammation Research, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Katie J SmithCentre for Inflammation Research, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Gareth HardistyCentre for Inflammation Research, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Adriano G RossiCentre for Inflammation Research, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.
Emily Gwyer FindlayCentre for Inflammation Research, College of Medicine and Veterinary Medicine, University of Edinburgh, Edinburgh, United Kingdom.

Funding

Medical Research Council MR/K013386/1
6 · The paper itself

Abstract

Neutrophils and T cells exist in close proximity in lymph nodes and inflamed tissues during health and disease. They are able to form stable interactions, with profound effects on the phenotype and function of the T cells. However, the outcome of these effects are frequently contradictory; in some systems neutrophils suppress T cell proliferation, in others they are activatory or present antigen directly. Published protocols modelling these interactions

Indexed as

Cell ProliferationCell CommunicationCells, CulturedCoculture TechniquesCytokinesHumansLymphocyte ActivationNeutrophilsT-LymphocytesCytokinesculture modelsinflammationneutrophilsPD1T cells

Identifiers

PMID33859639
PMCPMC8042376

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.