Evidence map›Paper›PMID 33859537›Full record

ArticleMediators of inflammation2021

Probiotic-Derived Polyphosphate Accelerates Intestinal Epithelia Wound Healing through Inducing Platelet-Derived Mediators.

Shotaro Isozaki, Hiroaki Konishi, Mikihiro Fujiya, Hiroki Tanaka, Yuki Murakami, Shin Kashima, Katsuyoshi Ando, Nobuhiro Ueno, Kentaro Moriichi, Toshikatsu Okumura

Open access · goldAbstract read
In one paragraph

Article in Mediators of inflammation, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
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  11. Article
  12. Antioxidants (Basel, Switzerland) · 2025
    Article
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  15. Article
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  17. The Current and Future Perspectives of Postbiotics.Probiotics and antimicrobial proteins · 2023
    Article
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  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Shotaro IsozakiDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Hiroaki KonishiDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Mikihiro FujiyaDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.ORCID https://orcid.org/0000-0002-4321-7774
Hiroki TanakaDivision of Tumor Pathology, Department of Pathology, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Yuki MurakamiDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Shin KashimaDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Katsuyoshi AndoDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Nobuhiro UenoDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Kentaro MoriichiDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Toshikatsu OkumuraDivision of Metabolism and Biosystemic Science, Gastroenterology, And Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Asahikawa 078-8510, Japan.
Asahikawa Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel disease (IBD), such as ulcerative colitis (UC) and Crohn's disease (CD), is an intractable intestinal inflammation associated with the disruption of the intestinal mucosa. We previously demonstrated that

Indexed as

AnimalsCells, CulturedExtracellular Signal-Regulated MAP KinasesIntestinal MucosaMiceMice, Inbred BALB CPlatelet ActivationPlatelet AggregationPolyphosphatesProbioticsWound HealingExtracellular Signal-Regulated MAP KinasesPolyphosphates

Identifiers

PMID33859537
PMCPMC8025129
OpenAlexW3151384802

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.