ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2021
The Triglyceride-Glucose Index is Associated with Diabetic Retinopathy in Chinese Patients with Type 2 Diabetes: A Hospital-Based, Nested, Case-Control Study.
Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- The triglyceride-glucose index as a biomarker of diabetic retinopathy: a systematic review and meta-analysis.Frontiers in medicine · 2025Pooled it
- Association between the triglyceride glucose index and diabetic retinopathy in type 2 diabetes: a meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Association between triglyceride-glucose index and diabetic retinopathy among patients with diabetes mellitus in Nepalese patients: a cross-sectional study.BMC endocrine disorders · 2026Observational
- Diabetic retinopathy: why some eyes suffer more - a focus on retina-specific risk factors and metabolic memory.Journal of translational medicine · 2026Review
- The triglyceride-glucose index for diabetic retinopathy prediction in Chinese patients with type 2 diabetes: a preliminary cross-sectional study.Frontiers in endocrinology · 2026Article
- Association between triglyceride glucose index related parameters and obstructive sleep apnea hypopnea syndrome in a cross sectional study.Scientific reports · 2025Article
- Correlation Between Triglyceride-Glucose Index and Microvascular Complications in Patients With Early- Onset of Type 2 Diabetes Mellitus.Endocrinology, diabetes & metabolism · 2025Article
- Review
- Development of machine learning predictive model for type 2 diabetic retinopathy using the triglyceride-glucose index explained by SHAP method.Frontiers in endocrinology · 2025Article
- Association of triglyceride glucose index with diabetic retinopathy in middle-aged and elderly ambulatory type 2 diabetic patients.Frontiers in endocrinology · 2025Article
- Association between triglyceride-glucose index and cataract among outpatient US adults.Frontiers in medicine · 2025Article
- An analysis of epidemiological characteristics of microvascular complications and comorbidities among type 1 diabetes patients.Acta biochimica Polonica · 2025Article
- 1-hour post-load plasma glucose: a reliable marker of insulin resistance in type 2 diabetes, as determined by the TyG index.Frontiers in endocrinology · 2025Article
- Elevated Triglyceride-Glucose Index as a Risk Stratification Marker for Diabetic Retinopathy in Type 2 Diabetes Mellitus: The Influence of Glycemic Control.Diabetes, metabolic syndrome and obesity : targets and therapy · 2025Article
- Sex-Based Differences in the Associations Between Obesity- and Lipid-Related Indexes and Hyperuricemia Risk in Patients with Obesity.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Article
- Role of Triglyceride-Glucose Index in Type 2 Diabetes Mellitus and Its Complications.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024Review
- Uric acid index is a risk for mild cognitive impairment in type 2 diabetes.Hormones (Athens, Greece) · 2023Observational
- Associations between fatty acid intake and diabetic retinopathy in a Japanese population.Scientific reports · 2023Article
- The U-Shape Relationship between Triglyceride-Glucose Index and the Risk of Diabetic Retinopathy among the US Population.Journal of personalized medicine · 2023Article
- Counterintuitive relationship between the triglyceride glucose index and diabetic foot in diabetes patients: A cross-sectional study.PloS one · 2023Article
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Authors and funding
13 authors.
Funding
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Abstract
backgroundThis study aimed to investigate the association between the triglyceride-glucose (TyG) index and diabetic retinopathy (DR) in Chinese patients with type 2 diabetes.
methodsIn this nested case-control study, all diabetic participants were registered hospitalizations during 2012-2018, including 596 with DR as cases and three matching controls per case. DR was assessed using Early Treatment Diabetic Retinopathy Study criteria. The TyG index was calculated: Ln (fasting blood glucose [mg/dL] × fasting triglycerides [mg/dL] ÷ 2). Multivariate logistic regression, a receiver-operating characteristic (ROC) curve, linear regression models, and mediation analysis were used to explore associations.
resultsThe TyG index was lower in DR and decreased as its severity advanced among 2,112 subjects (
conclusionThe TyG index was associated with the presence and severity of DR. Our findings suggest that the TyG index may become a useful biomarker in evaluating and following the presence of DR and VTDR.
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