SynthesisPediatric research2022
Physical and functional performance assessment in pediatric oncology: a systematic review.
Synthesis in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Effects of an Exercise Intervention on Gait Function in Young Survivors of Osteosarcoma with Megaendoprosthesis of the Lower Extremity-Results from the Pilot Randomized Controlled Trial proGAIT.Current oncology (Toronto, Ont.) · 2022Trial
- Physical activity and exercise in pediatric oncology: conceptual distinctions and clinical implications.Turkish journal of physical medicine and rehabilitation · 2026Article
- Gait and Functional Movement Quality Improvements Following an Individualized Exercise Program in Pediatric Hemato-Oncological Patients.Children (Basel, Switzerland) · 2026Article
- Multimodal Exercise and Nutritional Interventions in Pediatric Cancer: Effects on Physical Function, Body Composition, and Metabolic Health-A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Mapping Physical Fitness Assessments in Interventional Research Among Breast Cancer Survivors: A Scoping Review.Cancers · 2026Review
- Establish Global Nutrition Research Strategies: The Meeting Report of the First SIOP Nutrition Research Forum.Nutrients · 2026Article
- Self-Concept in Pediatric Cancer Patients.Advances in experimental medicine and biology · 2026Article
- Feasibility, uptake, and exploratory outcomes of an individualized exercise program in pediatric oncology: a prospective single-center pilot study.Frontiers in pediatrics · 2026Article
- Smart exercise in pediatric oncology: enhancing executive functions through cognitively challenging physical activity- a non-randomized controlled trial.BMC cancer · 2025Article
- Understanding kinesiophobia in pediatric bone tumors: investigating its presence and predictive factors.European journal of pediatrics · 2025Article
- Article
- Muscle strength, functional mobility, and performance in activities of daily living in children and adolescents with cancer.European journal of pediatrics · 2024Observational
- A Review of Late Effects in Pediatric Cancer: Implications for Rehabilitation.Rehabilitation oncology (American Physical Therapy Association. Oncology Section) · 2023Article
- Physical activity and physical fitness assessments in adolescents and young adults diagnosed with cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023Article
- Impaired aerobic capacity in adolescents and young adults after treatment for cancer or non-malignant haematological disease.Pediatric research · 2023Observational
- Is an Exercise Program for Pediatric Cancer Patients in Palliative Care Feasible and Supportive?-A Case Series.Children (Basel, Switzerland) · 2023Article
- Therapeutic exercise interventions in pediatric survivors of brain cancer and other solid tumors: A scoping review.Frontiers in pediatrics · 2022Article
- The Efficacy of Targeted Exercise on Gross Motor and Neuromuscular Performance in Survivors of Childhood Leukemia: A Pilot Study.Frontiers in pediatrics · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors at 12 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundResearch indicates reduced physical performance from diagnosis into survivorship of pediatric cancer patients. However, there is no systematic information or guideline available on the methods to assess physical performance and function in this population. The purpose was to systematically compile and describe assessments of physical performance and function in patients and survivors of pediatric cancer, including cardiorespiratory fitness, muscle strength, speed, balance, flexibility, functional mobility, gait and motor performance test batteries.
methodsWe searched the databases PubMed, SPORTDiscus, and Cochrane Database and performed abstract and full-text selection of 2619 articles according to the Cochrane Handbook of Systematic Reviews. Information on patients characteristics, assessments, information on validity and reliability, and relevant references was extracted.
resultsIn summary, 63 different assessments were found in 149 studies including 11639 participants. Most studies evaluated cardiorespiratory fitness and muscle strength with the majority conducted off treatment. Some outcomes (e.g. speed) and diagnoses (e.g. neuroblastoma) were severely underrepresented. With the exception of gait, leukemia patients represented the largest group of individuals tested.
conclusionsInsufficient data and patient heterogeneity complicate uniform recommendations for assessments. Our results support researchers and practitioners in selecting appropriate assessment to meet their specific research questions or individual daily practice needs. IMPACT: This systematic review includes 149 studies and provides a comprehensive summary of 63 assessments to evaluate cardiorespiratory fitness, muscle strength, speed, balance, flexibility, functional mobility, gait or motor performance test batteries in patients and survivors of pediatric cancer. We present the most studied fields within the pediatric cancer population, which are cardiorespiratory fitness and muscle strength, off treatment phase, and leukemia patients. We propose research priorities by identification of subgroups in terms of cancer type, phase of treatment, and outcome of interest that are underrepresented in studies currently available.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.