ArticleScientific reports2021
Exogenous enzymes and probiotics alter digestion kinetics, volatile fatty acid content and microbial interactions in the gut of Nile tilapia.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 97 citations in OpenAlex.
- Effects of Dietary Protein and Starch Digestion Rates on Jejunal and Cecal Microbial Community States and Feed Efficiency in Raccoon Dogs.Animals : an open access journal from MDPI · 2026Article
- Effects of carbohydrate sources on the physical quality of extrudate and their subsequent effects on feed intake, digestion and gut microbiota in spotted seabass (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2026Article
- Dietary rayon microfibers differentially reshape rearing water and host associated microbiomes of farmed European sea bass (Dicentrarchus labrax).Environmental microbiome · 2026Article
- Probiotic-based mycotoxin detoxification in poultry feed: mechanisms, efficacy, challenges, and future directions for sustainable production.Archives of microbiology · 2026Review
- Article
- Functional Benefits of Fermented Sesame Oilcake in the Diet of Nile Tilapia,Aquaculture nutrition · 2026Article
- Exogenous protease supplementation in high- and low-fishmeal diets for Pacific white shrimp (Animal nutrition (Zhongguo xu mu shou yi xue hui) · 2025Article
- Starvation Influences the Microbiota in the Stomach of the Corallivorous Crown-of-Thorns Starfish.Biology · 2025Article
- Effects of Microorganisms in Fish Aquaculture from a Sustainable Approach: A Review.Microorganisms · 2025Review
- Article
- Microalgae and phytase dietary supplementation improved growth and gut microbiota in juvenile European seabass (Dicentrarchus labrax).BMC genomics · 2024Article
- Biogas potential of organosolv pretreated wheat straw as mono and co-substrate: substrate synergy and microbial dynamics.Scientific reports · 2024Article
- Probiotics Alleviate Microcystin-LR-Induced Developmental Toxicity in Zebrafish Larvae.Toxics · 2024Article
- Article
- Synbiotic Agents and Their Active Components for Sustainable Aquaculture: Concepts, Action Mechanisms, and Applications.Biology · 2023Review
- Microbial inoculums improve growth and health of Heteropneustes fossilis via biofloc-driven aquaculture.Microbial cell factories · 2023Article
- Omics and imaging combinatorial approach reveals butyrate-induced inflammatory effects in the zebrafish gut.Animal microbiome · 2023Article
- In-Situ Biofloc Affects the Core Prokaryotes Community Composition in Gut and Enhances Growth of Nile Tilapia (Oreochromis niloticus).Microbial ecology · 2022Article
- Designing Biological Microsensors with Chiral Nematic Liquid Crystal Droplets.ACS applied materials & interfaces · 2022Article
- Improvement of Fish Growth and Metabolism by Oligosaccharide Prebiotic Supplement.Aquaculture nutrition · 2022Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sustainable aquafeed production requires fishmeal replacement, leading to an increasing use of plant-derived ingredients. As a consequence, higher levels of antinutritional substances, such as non-starch polysaccharides and phytate, are present in aquafeeds, with negative effects on fish performance, nutrient digestibility and overall gut health. To alleviate these negative effects, providing exogenous digestive enzymes and/or probiotics can be an effective solution. In this study, we tested the effect of dietary supplementation of enzymes (phytase and xylanase) and probiotics (three strains of Bacillus amyloliquefaciens) on nutrient digestion kinetics and volatile fatty acid content along the gut, and the distal gut microbiome diversity in Nile tilapia. Chyme volatile fatty content was increased with probiotic supplementation in the proximal gut, while lactate content, measured for the first time in vivo in fish, decreased with enzymes along the gut. Enzyme supplementation enhanced crude protein, Ca and P digestibility in proximal and middle gut. Enzymes and probiotics supplementation enhanced microbial interactions as shown by network analysis, while increased the abundance of lactic acid bacteria and Bacillus species. Such results suggest that supplementation with exogenous enzymes and probiotics increases nutrient availability, while at the same time benefits gut health and contributes to a more stable microbiome environment.
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