Evidence map›Paper›PMID 33859231›Full record

ArticleScientific reports2021

New phosphosite-specific antibodies to unravel the role of GRK phosphorylation in dopamine D

Anika Mann, Alastair C Keen, Hanka Mark, Pooja Dasgupta, Jonathan A Javitch, Meritxell Canals, Stefan Schulz, J Robert Lane

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Dopamine DJournal of medicinal chemistry · 2023
    Article
  9. Article
  10. Article
  11. PACInternational journal of molecular sciences · 2022
    Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 4 countries.

Anika Mann *Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Alastair C Keen *Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia.
Hanka MarkInstitute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Pooja DasguptaInstitute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany.
Jonathan A JavitchDepartments of Psychiatry and Pharmacology, Vagelos College of Physicians and Surgeons, Columbia University, New York, USA.
Meritxell CanalsDivision of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK.
Stefan SchulzInstitute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany. Stefan.Schulz@med.uni-jena.de.
J Robert LaneDivision of Physiology, Pharmacology and Neuroscience, School of Life Sciences, Queen's Medical Centre, University of Nottingham, Nottingham, UK. rob.lane@nottingham.ac.uk.
Friedrich Schiller University Jena · DEJena University Hospital · DEQueen's Medical Centre · GBNew York Psychoanalytic Society and Institute · USUniversity of Nottingham · GB

Funding

Structure of the Dopamine D2-Like Receptor Binding SitesR01MH054137 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI JAVITCH, JONATHAN A · 1995 to 2025
$12.0M
NIMH NIH HHS R01 MH054137
6 · The paper itself

Abstract

The dopamine D

Indexed as

AntibodiesArrestinsG-Protein-Coupled Receptor KinasesHEK293 CellsHumansMolecular Targeted TherapyParkinson DiseasePhosphorylationReceptors, Dopamine D2SchizophreniaSignal TransductionAntibodiesArrestinsG-Protein-Coupled Receptor KinasesReceptors, Dopamine D2

Identifiers

PMID33859231
PMCPMC8050214
OpenAlexW3152786958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.