ArticleScientific reports2021
Ultrasonic actuation of a fine-needle improves biopsy yield.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed.
- Ultrasound-enhanced fine-needle aspiration biopsy improves yield of solid benign parotid gland tumor tissue: a pilot study.European radiology experimental · 2026Article
- Investigation of Vibration-Induced Transport of Newtonian and Non-Newtonian Fluids in Porous Media Using Lattice Boltzmann Method.Bioengineering (Basel, Switzerland) · 2025Article
- ADAMTS5-specific gapmer release from an albumin biomolecular assembly and cartilage internalization triggered by ultrasound.Drug delivery · 2025Article
- Cavitation activity induced by spring-loaded core needle biopsy devices.Scientific reports · 2025Article
- Ultrasound-enhanced fine-needle biopsy improves tissue yield in head and neck tumors ex vivo.Scientific reports · 2025Article
- Needle bevel geometry influences the flexural deflection magnitude in ultrasound-enhanced fine-needle biopsy.Scientific reports · 2022Article
- Periodicity in ultrasonic atomization involving beads-fountain oscillations and mist generation: Effects of driving frequency.Ultrasonics sonochemistry · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Despite the ubiquitous use over the past 150 years, the functions of the current medical needle are facilitated only by mechanical shear and cutting by the needle tip, i.e. the lancet. In this study, we demonstrate how nonlinear ultrasonics (NLU) extends the functionality of the medical needle far beyond its present capability. The NLU actions were found to be localized to the proximity of the needle tip, the SonoLancet, but the effects extend to several millimeters from the physical needle boundary. The observed nonlinear phenomena, transient cavitation, fluid streams, translation of micro- and nanoparticles and atomization, were quantitatively characterized. In the fine-needle biopsy application, the SonoLancet contributed to obtaining tissue cores with an increase in tissue yield by 3-6× in different tissue types compared to conventional needle biopsy technique using the same 21G needle. In conclusion, the SonoLancet could be of interest to several other medical applications, including drug or gene delivery, cell modulation, and minimally invasive surgical procedures.
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