Evidence map›Paper›PMID 33859005›Full record

ArticleScience (New York, N.Y.)2021

Female-specific synaptic dysfunction and cognitive impairment in a mouse model of

Naosuke Hoshina, Erin M Johnson-Venkatesh, Miyuki Hoshina, Hisashi Umemori

Open access · greenAbstract read
In one paragraph

Article in Science (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.

  1. Pooled it
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  4. The intracellular domain of the epilepsy protein PCDH19 regulates spine density in cortical neurons in vivo viaThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
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  8. Zoological research · 2026
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Naosuke HoshinaDepartment of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID https://orcid.org/0000-0003-2575-1356
Erin M Johnson-VenkateshDepartment of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.ORCID https://orcid.org/0000-0003-2590-0737
Miyuki HoshinaDepartment of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Hisashi UmemoriDepartment of Neurology, F. M. Kirby Neurobiology Center, Boston Children's Hospital, Harvard Medical School, Boston, MA 02115, USA. hisashi.umemori@childrens.harvard.edu.ORCID https://orcid.org/0000-0001-7198-2062
Boston Children's Hospital · US

Funding

Finding the projection-specific dopaminergic synaptic organizersR01DA042744 · NIDA · BOSTON CHILDREN'S HOSPITAL · PI Hisashi Umemori, Mitsuko Watabe-Uchida · 2017 to 2026
$3.9M
NIDA NIH HHS R01 DA042744
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Animalsbeta CateninCA3 Region, HippocampalCadherinsCognitive DysfunctionDisease Models, AnimalEpilepsyFemaleGenes, X-LinkedGenetic Diseases, X-LinkedLong-Term PotentiationMaleMiceMossy Fibers, HippocampalMutationProtocadherinsbeta CateninCadherinsCdh2 protein, mousePcdh19 protein, mouseProtocadherins

Identifiers

PMID33859005
PMCPMC9873198
OpenAlexW3154601095

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.