ArticleClinical cancer research : an official journal of the American Association for Cancer Research2021
Development and Validation of a Novel Nomogram for Individualized Prediction of Survival in Cancer of Unknown Primary.
Article in Clinical cancer research : an official journal of the American Association for Cancer Research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
- Nomogram for prognosis of patients with esophageal squamous cell cancer after minimally invasive esophagectomy established based on non-textbook outcome.Surgical endoscopy · 2022Trial
- Integrating artificial intelligence into cancers of unknown primary diagnosis and treatment.iScience · 2026Review
- Article
- Integrating clinicopathologic factors with whole-exome sequencing and peripheral immune repertoire sequencing to optimize decision-making in neoadjuvant chemoimmunotherapy for HNSCC.Frontiers in immunology · 2026Article
- Cancer of unknown primary genomic profiling from cell-free DNA provides insights into CUP biology and vulnerabilities.Frontiers in medicine · 2026Article
- Development and validation of a nomogram for predicting hospitalization-associated disability in older patients with acute heart failure.Frontiers in cardiovascular medicine · 2026Article
- Nomogram predicting overall survival in hospitalized cervical cancer patients in Mato Grosso, Brazil.Discover oncology · 2025Article
- Skeletal Muscle Density as a Predictor of Prognosis and Physical Reserve in Patients with Cancer of Unknown Primary.Journal of clinical medicine · 2025Article
- Development and external validation of a nomogram for choosing postoperative adjuvant therapies in uterine sarcoma patients using real-world data.Frontiers in oncology · 2025Article
- The clinical validity of radiomics-based prediction of molecular subtypes in breast cancer from digital mammary tomosynthesis.Frontiers in oncology · 2025Article
- Evaluation of conditional survival outcomes in patients with redefined anaplastic thyroid carcinoma.Frontiers in endocrinology · 2025Article
- Analysis of the ideal cutoff age as a predictor of differentiated thyroid cancer using the Surveillance, Epidemiology, and End Results database.Translational cancer research · 2024Article
- Screening high-risk individuals for primary gastric carcinoma: evaluating overall survival probability score in the presence and absence of lymphatic metastasis post-gastrectomy.World journal of surgical oncology · 2024Article
- Clinical outcome and prognostic factors of T4N0M0 colon cancer after R0 resection: A retrospective study.World journal of gastrointestinal oncology · 2024Article
- The Nomogram Model and Factors for the Postoperative Mortality of Elderly Patients with Femoral Neck Fracture Undergoing Artificial Hip Arthroplasty: A Single-Institution 6-Year Experience.Orthopaedic surgery · 2024Article
- Development and validation of a nomogram to predict medication risk based on a knowledge, attitude and practice (KAP) survey of residents in Shanxi Province, China.Frontiers in pharmacology · 2024Article
- Cost-effective prognostic evaluation of breast cancer: using a STAR nomogram model based on routine blood tests.Frontiers in endocrinology · 2024Article
- Comprehensive analysis of cancer of unknown primary and recommendation of a histological and immunohistochemical diagnostic strategy from China.BMC cancer · 2023Article
- Hub genes and their key effects on prognosis of Burkitt lymphoma.World journal of clinical oncology · 2023Article
- Prediction model for lymph node metastasis in superficial colorectal cancer: a better choice than computed tomography.Surgical endoscopy · 2023Article
Corrections and comments
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Authors and funding
17 authors.
Funding
Abstract
purposePrognostic uncertainty is a major challenge for cancer of unknown primary (CUP). Current models limit a meaningful patient-provider dialogue. We aimed to establish a nomogram for predicting overall survival (OS) in CUP based on robust clinicopathologic prognostic factors. EXPERIMENTAL
designWe evaluated 521 patients with CUP at MD Anderson Cancer Center (MDACC; Houston, TX; 2012-2016). Baseline variables were analyzed using Cox regression and nomogram developed using significant predictors. Predictive accuracy and discriminatory performance were assessed by calibration curves, concordance probability estimate (CPE ± SE), and concordance statistic (C-index). The model was subjected to bootstrapping and multi-institutional external validations using two independent CUP cohorts: V1 [MDACC (2017),
resultsBaseline characteristics of entire cohort (
conclusionsOur user-friendly CUP nomogram integrating commonly available baseline factors provides robust personalized prognostication which can aid clinical decision making and selection/stratification for clinical trials.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.