Evidence map›Paper›PMID 33858556›Full record

ReviewJournal of the International Neuropsychological Society : JINS2022

Central Nervous System Manifestations of COVID-19: A Critical Review and Proposed Research Agenda.

Kelsey C Hewitt, David E Marra, Cady Block, Lucette A Cysique, Daniel L Drane, Michelle M Haddad, Emilia Łojek, Carrie R McDonald, Anny Reyes, Kara Eversole and 1 more

Open access · greenAbstract readReview
In one paragraph

Review in Journal of the International Neuropsychological Society : JINS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Brain histopathological changes caused by SARS-CoV-2 infection.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 3 countries.

Kelsey C HewittEmory University School of Medicine, Department of Neurology, Atlanta, GA30329, USA.ORCID 0000-0003-1448-2664
David E MarraUniversity of Florida, Department of Clinical and Health Psychology, Gainesville, FL32610, USA.ORCID 0000-0002-7392-6555
Cady BlockEmory University School of Medicine, Department of Neurology, Atlanta, GA30329, USA.ORCID 0000-0001-7168-6116
Lucette A CysiqueUniversity of New South Wales, Department of Psychology, The Alfred Hospital, Melbourne, 3004, Australia.ORCID 0000-0002-7711-6373
Daniel L DraneEmory University School of Medicine, Department of Neurology, Atlanta, GA30329, USA.
Michelle M HaddadEmory University, Department of Rehabilitation Medicine, Atlanta, GA30329, USA.
Emilia ŁojekUniversity of Warsaw, Department of Psychology, Warszawa, 00-183, Poland.
Carrie R McDonaldUniversity of California-San Diego, Department of Psychiatry, La Jolla, CA92093, USA.
Anny ReyesUniversity of California-San Diego, Department of Psychiatry, La Jolla, CA92093, USA.
Kara EversoleJames Madison University, Department of Graduate Psychology, Harrisonburg, VA22807, USA.
Dawn BowersUniversity of Florida, Department of Clinical and Health Psychology, Gainesville, FL32610, USA.
Emory University · USUniversity of California San Diego · USUniversity of Florida Health · USJames Madison University · USThe Alfred Hospital · AUUniversity of Warsaw · PL

Funding

Using social networks to map and evaluate team science across CTSA hubsUL1TR001427 · NCATS · UNIVERSITY OF FLORIDA · PI MITCHELL, DUANE A. · 2015 to 2024
$37.2M
National Neuropsychological Network (NNN)R01MH118514 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DANIEL L DRANE, David W. Loring · 2019 to 2026
$9.4M
Dissecting the Cognitive Roles of Hippocampus, Other Temporal Lobe StructuresR01NS088748 · NINDS · EMORY UNIVERSITY · PI DRANE, DANIEL L · 2014 to 2024
$6.4M
Multimodal Imaging of Language in the Preoperative Evaluation of EpilepsyR01NS065838 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCDONALD, CARRIE R · 2010 to 2018
$4.4M
Revitalizing Cognition in Older Adults at Risk for Alzheimer's Disease with Near-Infrared Photobiomodulation: Diversity SupplementR01AG064587 · NIA · UNIVERSITY OF FLORIDA · PI ALEXANDER, GENE E, BOWERS, DAWN · 2019 to 2023
$4.0M
Interdisciplinary Training in Movement Disorders and NeurorestorationT32NS082168 · NINDS · UNIVERSITY OF FLORIDA · PI Melissa Jo Armstrong, David E Vaillancourt · 2015 to 2026
$2.8M
Multimodal imaging of memory reorganization in epilepsy from whole brain networks to local neuronal responses: Implications for surgical-decision-makingR56NS065838 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MCDONALD, CARRIE R · 2020 to 2020
$467k
Prediction of seizure lateralization and postoperative outcome through the use of deep learning applied to multi-site MRI/DTI data: An ENIGMA-Epilepsy studyR21NS107739 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BONILHA, LEONARDO F, MCDONALD, CARRIE R · 2019 to 2019
$444k
Determining Plasticity of Brain-Regulatory Mechanisms Related to Emotion Processing: A Neurofeedback Approach in Aging and Parkinson DiseaseR21AG057200 · NIA · UNIVERSITY OF FLORIDA · PI BOWERS, DAWN, EBNER, NATALIE C · 2017 to 2018
$419k
Explaining cognitive heterogeneity in temporal lobe epilepsy (TLE): Identifying unique imaging features, health-related risk factors and protective factors in TLE subtypesF31NS111883 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI REYES, ANNY · 2019 to 2021
$89k
NCATS NIH HHS UL1 TR001427NIA NIH HHS R01 AG064587NIA NIH HHS R21 AG057200NIMH NIH HHS R01 MH118514NINDS NIH HHS F31 NS111883NINDS NIH HHS R01 NS065838NINDS NIH HHS R01 NS088748NINDS NIH HHS R21 NS107739NINDS NIH HHS R56 NS065838NINDS NIH HHS T32 NS082168
6 · The paper itself

Abstract

objectiveOn March 11, 2020, the World Health Organization declared an outbreak of a new viral entity, coronavirus 2019 (COVID-19), to be a worldwide pandemic. The characteristics of this virus, as well as its short- and long-term implications, are not yet well understood. The objective of the current paper was to provide a critical review of the emerging literature on COVID-19 and its implications for neurological, neuropsychiatric, and cognitive functioning.

methodA critical review of recently published empirical research, case studies, and reviews pertaining to central nervous system (CNS) complications of COVID-19 was conducted by searching PubMed, PubMed Central, Google Scholar, and bioRxiv.

resultsAfter considering the available literature, areas thought to be most pertinent to clinical and research neuropsychologists, including CNS manifestations, neurologic symptoms/syndromes, neuroimaging, and potential long-term implications of COVID-19 infection, were reviewed.

conclusionOnce thought to be merely a respiratory virus, the scientific and medical communities have realized COVID-19 to have broader effects on renal, vascular, and neurological body systems. The question of cognitive deficits is not yet well studied, but neuropsychologists will undoubtedly play an important role in the years to come.

Indexed as

COVID-19Central Nervous SystemHumansPandemicsSARS-CoV-2BrainCognitionCognitive functionCoronavirusMental healthNeuropsychology

Identifiers

PMID33858556
PMCPMC10035233
OpenAlexW3152862061

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.