ArticleInfectious diseases of poverty2021
Epidemiology of dengue virus infections in Nepal, 2006-2019.
Article in Infectious diseases of poverty, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Epidemiology of dengue in SAARC territory: a systematic review and meta-analysis.Parasites & vectors · 2022Pooled it
- Unravelling the distribution of vectors of major vector-borne diseases in Koshi Province of Nepal: A concern of expansion in diverse geo-ecological and climatic regions.PLoS neglected tropical diseases · 2026Article
- Unveiling the Dengue Knowledge Gap and Symptom Awareness Among Students of Shahjalal University of Science and Technology, Sylhet: A Cross-Sectional Study.Health science reports · 2026Article
- Diversity of dengue virus serotypes in Nepal during the 2022 outbreak.Tropical medicine and health · 2025Article
- Service readiness of primary healthcare facilities for dengue management in Bagmati Province, Nepal: a mixed method study.Journal of public health (Oxford, England) · 2025Article
- Dengue Fever Resurgence in Iran: An Integrative Review of Causative Factors and Control Strategies.Tropical medicine and infectious disease · 2025Review
- Differential Impacts of Extreme Weather Events on Vector-Borne Disease Transmission Across Urban and Rural Settings: A Scoping Review.Healthcare (Basel, Switzerland) · 2025Review
- Clinical observations and outcomes of dengue-associated retinopathy at a tertiary eye hospital in Nepal.BMC ophthalmology · 2025Observational
- Transforming health in Nepal: a historical and contemporary review on disease burden, health system challenges, and innovations.Health research policy and systems · 2025Review
- Epidemiological and Geographical Factors Associated with Dengue in Bangladesh: A Multicenter Study of the 2023 Dengue Epidemic.The American journal of tropical medicine and hygiene · 2025Article
- Leukopenia and thrombocytopenia in dengue patients presenting in the emergency department of a tertiary center in Nepal: a cross-sectional study.BMC infectious diseases · 2025Article
- Exploring policy processes against microbial threats in Iran: a qualitative policy analysis.BMJ open · 2025Article
- On people's perceptions of climate change and its impacts in a hotspot of global warming.PloS one · 2025Article
- Increased thermal suitability elevates the risk of dengue transmission across the mid hills of Nepal.PloS one · 2025Article
- Climate-driven dengue fever outbreaks in Nepal: Trends, challenges, and strategies.World journal of virology · 2024Article
- Clinical and laboratory comparison of severe (Group B and C) Dengue cases with molecular characterization from 2019 epidemics in Dhaka, Bangladesh.PLoS neglected tropical diseases · 2024Article
- Dengue virus surveillance in Nepal yields the first on-site whole genome sequences of isolates from the 2022 outbreak.BMC genomics · 2024Article
- Article
- Feasibility of NepaDengue mobile application for dengue prevention and control: user and stakeholder perspectives in Nepal.BMJ public health · 2024Article
- Severe dengue infection unmasking drug-induced liver injury: Successful management with N-acetylcysteine.Clinical case reports · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDengue is one of the newest emerging diseases in Nepal with increasing burden and geographic spread over the years. The main objective of this study was to explore the epidemiological patterns of dengue since its first outbreak (2006) to 2019 in Nepal.
methodsThis study is a retrospective analysis that covers the last 14 years (2006-2019) of reported dengue cases from Epidemiology Diseases Control Division (EDCD), Ministry of Health and Population, Government of Nepal. Reported cases were plotted over time and maps of reported case incidence were generated (from 2016 through 2019). An ecological analysis of environmental predictors of case incidence was conducted using negative binomial regression.
resultsWhile endemic dengue has been reported in Nepal since 2006, the case load has increased over time and in 2019 a total of 17 992 dengue cases were reported from 68 districts (from all seven provinces). Compared to the case incidence in 2016, incidence was approximately five times higher in 2018 [incidence rate ratio (IRR): 4.8; 95% confidence interval (CI) 1.5-15.3] and over 140 times higher in 2019 (IRR: 141.6; 95% CI 45.8-438.4). A one standard deviation increase in elevation was associated with a 90% decrease in reported case incidence (IRR: 0.10; 95% CI 0.01-0.20). However, the association between elevation and reported cases varied across the years. In 2018 there was a cluster of cases reported from high elevation Kaski District of Gandaki Province. Our results suggest that dengue infections are increasing in magnitude and expanding out of the lowland areas to higher elevations over time.
conclusionsThere is a high risk of dengue outbreak in the lowland Terai region, with increasing spread towards the mid-mountains and beyond as seen over the last 14 years. Urgent measures are required to increase the availability of diagnostics and resources to mitigate future dengue epidemics.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.