Observational studyJournal of cardiothoracic surgery2021
Association between glucose variability and postoperative delirium in acute aortic dissection patients: an observational study.
Observational study in Journal of cardiothoracic surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
28 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Diabetes mellitus is associated with an increased risk of postoperative neurocognitive disorders: a systematic review.Frontiers in medicine · 2026Pooled it
- Risk factors for postoperative delirium in patients with Stanford type A aortic dissection: a systematic review and meta-analysis.Journal of cardiothoracic surgery · 2024Pooled it
- Association Between the Hemoglobin Glycation Index and the Risk of Delirium in Stroke Patients Admitted to the Intensive Care Unit: A Retrospective Study Based on the MIMIC-IV Database.Brain and behavior · 2026Article
- Association between hemoglobin glycation index and delirium after gastric surgery: Based upon the MIMIC-IV.Medicine · 2026Article
- Development and validation of a nomogram-based risk prediction model for postoperative delirium in patients with stanford type A aortic dissection.Journal of cardiothoracic surgery · 2026Observational
- Incidence, predictors and outcomes of delirium in acute aortic syndrome.Journal of cardiothoracic surgery · 2026Article
- Article
- Association between stress hyperglycemia ratio and post-stroke delirium in critically ill patients with ischemic stroke: an MIMIC-IV database analysis.European journal of medical research · 2025Article
- A simple ratio, a complex outcome: glucose-to-albumin ratio predicts delirium in ICU patients after cardiac surgery.BMC cardiovascular disorders · 2025Article
- The Association Between Frequency of Fingertip Blood Glucose Measurement and Delirium in Intensive Care Unit Patients: A Retrospective Study Based on the MIMIC-IV Database.Nursing in critical care · 2025Article
- Systematic Review and Meta-analysis of Admission Inflammatory Biomarkers for Evaluating Prognosis in Acute Type A Aortic Dissection.Aorta (Stamford, Conn.) · 2025Article
- A correlational study of plasma galectin-3 as a potential predictive marker of postoperative delirium in patients with acute aortic dissection.Scientific reports · 2025Observational
- The Role of Stress Hyperglycemia on Delirium Onset.Journal of clinical medicine · 2025Review
- Prognostic impact of the metabolic syndrome and its components in acute type a aortic dissection after surgery: a retrospective study.Journal of cardiothoracic surgery · 2024Article
- Quantitative Electroencephalography for Predication of Neurological Dysfunction in Type A Aortic Dissection: A Prospective Observational Study.Journal of the American Heart Association · 2024Observational
- Association between preoperative persistent hyperglycemia and postoperative delirium in geriatric hip fracture patients.BMC geriatrics · 2024Article
- Continuous Glucose Monitoring in Older Adults: What We Know and What We Have Yet to Learn.Journal of diabetes science and technology · 2024Review
- Relative band power in assessing temporary neurological dysfunction post- type A aortic dissection surgery: a prospective study.Scientific reports · 2024Observational
- Clinical Significance of the Prognostic Nutritional Index in Predicting Delirium among Critically Ill Patients: A Retrospective Cohort Study.Critical care research and practice · 2024Article
- Systematic review and meta-analysis of the risk factors for postoperative delirium in patients with acute type A aortic dissection.Journal of thoracic disease · 2023Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundBlood glucose variability is associated with poor prognosis after cardiac surgery, but the relationship between glucose variability and postoperative delirium in patients with acute aortic dissection is unclear. The study aims to investigate the association of blood glucose variability with postoperative delirium in acute aortic dissection patients.
methodsWe prospectively analyzed 257 patients including 103 patients with delirium. The patients were divided into two groups according to whether delirium was present. The outcome measures were postoperative delirium, the length of the Intensive Care Unit stay, and the duration of hospital stay. Multivariable Cox competing risk survival models was used to assess.
resultsA total of 257 subjects were enrolled, including 103 patients with delirium. There were statistically significant differences between the two groups in body mass index, history of cardiac surgery, first admission blood glucose, white blood cell counts, Acute Physiology and Chronic Health Evaluation II score, hypoxemia, mechanical ventilation duration, and the length of Intensive Care Unit stay(P < 0.05). The delirium group exhibited significantly higher values of the mean of blood glucose (MBG) and the standard deviation of blood glucose (SDBG) than in the non-delirium group(P < 0.05). In model 1, the adjusted hazard ratio (AHR) of the standard deviation of blood glucose was 1.436(P < 0.05). In Model 2, the standard deviation of blood glucose (AHR = 1.418, 95%CI = 1.195-1.681, P < 0.05) remained significant after adjusting for confounders. The area under the curve of the SDBG was 0.763(95%CI = 0.704-0.821, P < 0.01). The sensitivity was 81.6%, and the specificity was 57.8%.
conclusionsGlucose variability is associated with the risk of delirium in patients after aortic dissection surgery, and high glycemic variability increases the risk of postoperative delirium.
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