Evidence map›Paper›PMID 33858446›Full record

ArticleMalaria journal2021

Malaria in pregnancy complications in Southern Venezuela.

Mariestéfany Romero, Elízabeth Leiba, Fhabián S Carrión-Nessi, Diana C Freitas-De Nobrega, Serris Kaid-Bay, Ángel F Gamardo, Melynar Chavero, Luisamy Figuera, Natasha A Camejo-Ávila, María V Marcano and 2 more

Open access · goldAbstract read
In one paragraph

Article in Malaria journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Malaria signs, symptoms, prevention knowledge and its associated factors among rural Ethiopians.African journal of primary health care & family medicine · 2025
    Article
  3. Current update on malaria in pregnancy: a systematic review.Tropical diseases, travel medicine and vaccines · 2025
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Infections and Pregnancy: Effects on Maternal and Child Health.Frontiers in cellular and infection microbiology · 2022
    Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Mariestéfany Romero *"Dr. Francisco Battistini Casalta" Health Sciences School, University of Oriente - Bolivar Nucleus, Ciudad Bolivar, Venezuela.
Elízabeth Leiba *"Dr. Francisco Battistini Casalta" Health Sciences School, University of Oriente - Bolivar Nucleus, Ciudad Bolivar, Venezuela.
Fhabián S Carrión-Nessi"Dr. Francisco Battistini Casalta" Health Sciences School, University of Oriente - Bolivar Nucleus, Ciudad Bolivar, Venezuela.
Diana C Freitas-De Nobrega"Dr. Francisco Battistini Casalta" Health Sciences School, University of Oriente - Bolivar Nucleus, Ciudad Bolivar, Venezuela.
Serris Kaid-BayGynaecology and Obstetrics Department, "Ruíz y Páez" University Hospital Complex, Ciudad Bolivar, Venezuela.
Ángel F GamardoBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Melynar ChaveroBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Luisamy FigueraBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Natasha A Camejo-ÁvilaBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
María V MarcanoBiomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela.
Mary Lopez-Perez *Centre for Medical Parasitology, Department of Immunology and Microbiology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
David A Forero-Peña *Biomedical Research and Therapeutic Vaccines Institute, Ciudad Bolivar, Venezuela. vacter.cv@gmail.com.
Universidad de Oriente · VEUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPregnant women are particularly vulnerable to malaria infections, increasing the risk of maternal-fetal complications, mainly in high-endemicity areas. However, few studies of malaria in pregnancy (MiP) have been carried out in Latin America, a region with low endemicity and transmission of both, Plasmodium falciparum and Plasmodium vivax. Despite the high malaria burden in Venezuela in the last years, no recent studies of MiP have been conducted. Hence, epidemiological and clinical characteristics of pregnant women with malaria in southern Venezuela are described herein.

methodsA retrospective study in pregnant women attending at the "Ruíz y Páez" University Hospital Complex, Bolivar state, Venezuela, was carried out between February and October, 2019. Epidemiological, clinical, and laboratory information was analysed.

resultsThirty-seven out of 52 pregnant women analysed were infected with P. vivax. Age ranged between 15 and 39 years, and adolescent pregnancies were common. Malaria infection was diagnosed mainly during the third trimester of pregnancy (63.4%). The distribution of symptoms and signs as well as clinical laboratory values was similar among Plasmodium spp. Although uncomplicated malaria was most frequent, 30% (13/52) had severe anaemia. A high proportion of studied women (44%) presented at least one complication during the pregnancy or delivery. Spontaneous abortion was recorded in four women, and three fetal deaths were observed. Six women had preterm delivery without any further complication.

conclusionsA high prevalence of maternal-fetal complications was found in the studied population, highlighting the requirement for a careful medical follow up during the prenatal check-ups, which should include routinary malaria tests. Preventive measures as distribution of insecticide-treated mosquito net for pregnant women at risk should also be implemented. Those measures can help to reduce the negative impact of malaria on the newborn and mother.

Indexed as

AdolescentAdultFemaleHumansMalaria, FalciparumMalaria, VivaxPlasmodium falciparumPlasmodium vivaxPregnancyPregnancy Complications, ParasiticRetrospective StudiesVenezuelaYoung AdultMalariaPlasmodium falciparumPlasmodium vivaxPregnancyVenezuela

Identifiers

PMID33858446
PMCPMC8051027
OpenAlexW3154314046

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.