ArticleJournal of translational medicine2021
Sulfur amino acid restriction, energy metabolism and obesity: a study protocol of an 8-week randomized controlled dietary intervention with whole foods and amino acid supplements.
Article in Journal of translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Dietary sulfur amino acid restriction in humans with overweight and obesity: a translational randomized controlled trial.Journal of translational medicine · 2024Trial
- Cognitive Effects of Taurine and Related Sulphur-Containing Amino Acids: A Systematic Review of Human Trials and Considerations for Plant-Based Dietary Transitions.Foods (Basel, Switzerland) · 2026Review
- Redox-dependent pathways in the pro-thermogenic effects of cysteine restriction.Nature metabolism · 2025Article
- Article
- Dietary methionine restriction started late in life promotes healthy aging in a sex-specific manner.Science advances · 2025Article
- Article
- A Comprehensive Review on Harnessing Soy Proteins in the Manufacture of Healthy Foods through Extrusion.Foods (Basel, Switzerland) · 2024Review
- GCN2 is required to maintain core body temperature in mice during acute cold.American journal of physiology. Endocrinology and metabolism · 2023Article
- Cysteine-lowering treatment with mesna against obesity: Proof of concept and results from a human phase I, dose-finding study.Diabetes, obesity & metabolism · 2023Article
- Associations between plasma sulfur amino acids and specific fat depots in two independent cohorts: CODAM and The Maastricht Study.European journal of nutrition · 2023Article
- The association of fasting plasma thiol fractions with body fat compartments, biomarker profile, and adipose tissue gene expression.Amino acids · 2023Article
- Ruminococcaceae_UCG-013 Promotes Obesity Resistance in Mice.Biomedicines · 2022Article
- The association of serum sulfur amino acids and related metabolites with incident diabetes: a prospective cohort study.European journal of nutrition · 2022Article
- The relationship between dietary sulfur amino acids intake and severity and frequency of pain in Iranian patients with musculoskeletal pains, 2020.BMC research notes · 2022Article
- Intestinal effect of faba bean fractions in WD-fed mice treated with low dose of DSS.PloS one · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 5 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDietary sulfur amino acid (SAA) restriction is an established animal model for increasing lifespan and improving metabolic health. Data from human studies are limited. In the study outlined in this protocol, we will evaluate if dietary SAA restriction can reduce body weight and improve resting energy expenditure (REE) and parameters related to metabolic health. METHOD/
designMen and women (calculated sample size = 60), aged 18-45 years, with body mass index of 27-35 kg/m DISCUSSION: The strength of this study is the randomized double-blind design. A limitation is the restrictive nature of the diet which may lead to poor compliance. If this study reveals a beneficial effect of the SAA
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Registered trials
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