Evidence map›Paper›PMID 33858356›Full record

ArticleBMC geriatrics2021

The incidence of mental disorder increases after hip fracture in older people: a nationwide cohort study.

Ling-Yin Kuo, Po-Ting Hsu, Wen-Tien Wu, Ru-Ping Lee, Jen-Hung Wang, Hao-Wen Chen, Ing-Ho Chen, Tzai-Chiu Yu, Cheng-Huan Peng, Kuan-Lin Liu and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Brain-Bone Axis in Physiological and Pathological Conditions.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Ling-Yin Kuo *School of Medicine, Tzu Chi University, Hualien, Taiwan.
Po-Ting Hsu *School of Medicine, Tzu Chi University, Hualien, Taiwan.
Wen-Tien WuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Ru-Ping LeeInstitute of Medical Sciences, Tzu Chi University, Hualien, Taiwan.
Jen-Hung WangDepartment of Medical Research, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan.
Hao-Wen ChenDepartment of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 707, ChungYang Rd., Hualien, Taiwan.
Ing-Ho ChenSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Tzai-Chiu YuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Cheng-Huan PengDepartment of Orthopedics, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, No. 707, ChungYang Rd., Hualien, Taiwan.
Kuan-Lin LiuSchool of Medicine, Tzu Chi University, Hualien, Taiwan.
Chung-Yi HsuGraduate Institute of Clinical Medical Science, China Medical University, Taichung, Taiwan.
Kuang-Ting YehSchool of Medicine, Tzu Chi University, Hualien, Taiwan. micrograft@tzuchi.com.tw.
Tzu Chi Foundation · TWTzu Chi University · TWHualien Tzu Chi Medical Center · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople living with dementia seem to be more likely to experience delirium following hip fracture. The association between mental disorders (MD) and hip fracture remains controversial. We conducted a nationwide study to examine the prevalence of MD in geriatric patients with hip fractures undergoing surgery and conducted a related risk factor analysis. MATERIAL AND

methodsThis retrospective cohort study used data from Taiwan's National Health Insurance Research Database between 2000 and 2012 and focused on people who were older than 60 years. Patients with hip fracture undergoing surgical intervention and without hip fracture were matched at a ratio of 1:1 for age, sex, comorbidities, and index year. The incidence and hazard ratios of age, sex, and multiple comorbidities related to MD and its subgroups were calculated using Cox proportional hazards regression models.

resultsA total of 1408 patients in the hip fracture group and a total of 1408 patients in the control group (no fracture) were included. The overall incidence of MD for the hip fracture and control groups per 100 person-years were 0.8 and 0.5, respectively. Among MD, the incidences of transient MD, depression, and dementia were significantly higher in the hip fracture group than in the control group.

conclusionsThe prevalence of newly developed MD, especially transient MD, depression, and dementia, was higher in the geriatric patients with hip fracture undergoing surgery than that in the control group. Prompt and aggressive prevention protocols and persistent follow-up of MD development is highly necessary in this aged society.

Indexed as

Hip FracturesAgedAged, 80 and overCohort StudiesHumansIncidenceProportional Hazards ModelsRetrospective StudiesRisk FactorsTaiwanDementiaDepressionGeriatric hip fractureNationwide cohort-based studyTransient mental disorder

Identifiers

PMID33858356
PMCPMC8051058
OpenAlexW3153702379

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.