Evidence map›Paper›PMID 33858251›Full record

SynthesisThe Journal of international medical research2021

Meta-analysis reveals significant association between

Guiqin Tan, Xin Wang, Guangbing Zheng, Juan Du, Fangyu Zhou, Zhongzhi Liang, Wenwen Wei, Hongsong Yu

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in The Journal of international medical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. International journal of molecular sciences · 2026
    Review
  2. Review
  3. Review
  4. Article
  5. Reply.Turkish journal of ophthalmology · 2024
    Article
  6. Genetic and Epigenetic Association ofInternational journal of molecular sciences · 2024
    Article
  7. The Role ofTurkish journal of ophthalmology · 2024
    Article
  8. Crucial Role ofDiagnostics (Basel, Switzerland) · 2023
    Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Guiqin TanDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Xin WangDepartment of Basic Medical Education, Zunyi Medical University, Zunyi, China.
Guangbing ZhengDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Juan DuDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Fangyu ZhouDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Zhongzhi LiangDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Wenwen WeiDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.
Hongsong YuDepartment of Immunology, Special Key Laboratory of Gene Detection and Therapy of Guizhou Province, Zunyi Medical University, Zunyi, China.ORCID https://orcid.org/0000-0002-1209-2104
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis meta-analysis aimed to determine the associations between the rs3761547, rs3761548, and rs3761549 single-nucleotide polymorphisms (SNPs) of the forkhead box P3 (

methodsCase-control studies with information on the associations between the rs3761547, rs3761548, and rs3761549

resultsSeven independent case-control studies including 4051 GD patients and 4569 controls were included in the meta-analysis. The overall pooled analysis indicated that

conclusionThis meta-analysis demonstrated that

Indexed as

Forkhead Transcription FactorsGenetic Predisposition to DiseaseGraves DiseaseChinaHumansPolymorphism, Single NucleotideForkhead Transcription FactorsFOXP3 protein, humanethnicityFOXP3Graves’ diseasemeta-analysispolymorphismsusceptibility

Identifiers

PMID33858251
PMCPMC8054215
OpenAlexW3154753639

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.