Evidence map›Paper›PMID 33858216›Full record

ArticleTissue engineering. Part A2021

Investigation of a Prevascularized Bone Graft for Large Defects in the Ovine Tibia.

Yunzhi Peter Yang, Benjamin C Gadomski, Arnaud Bruyas, Jeremiah Easley, Kevin M Labus, Brad Nelson, Ross H Palmer, Holly Stewart, Kirk McGilvray, Christian M Puttlitz and 8 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tissue engineering. Part A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Journal of orthopaedic translation · 2022
    Article
  5. Probing the role of methyl methacrylate release from spacer materials in induced membrane bone healing.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2022
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 2 institutions in 1 country.

Yunzhi Peter YangDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Benjamin C GadomskiDepartment of Mechanical Engineering and School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.
Arnaud BruyasDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Jeremiah EasleyDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Kevin M LabusDepartment of Mechanical Engineering and School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.
Brad NelsonDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Ross H PalmerDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Holly StewartDepartment of Clinical Sciences, Colorado State University, Fort Collins, Colorado, USA.
Kirk McGilvrayDepartment of Mechanical Engineering and School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.
Christian M PuttlitzDepartment of Mechanical Engineering and School of Biomedical Engineering, Colorado State University, Fort Collins, Colorado, USA.
Dan ReganDepartment of Microbiology, Immunology, and Pathology, Colorado State University, Fort Collins, Colorado, USA.
Alexander StahlDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Elaine LuiDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Jiannan LiDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Seyedsina MoeinzadehDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Sungwoo KimDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
William MaloneyDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Michael J GardnerDepartment of Orthopaedic Surgery, Stanford University, Stanford, California, USA.
Stanford University · USColorado State University · US

Funding

Microengineered Osteons for Bone Tissue EngineeringR01AR057837 · NIAMS · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI YANG, YUNZHI · 2010 to 2018
$5.1M
Systems Modeling Guided Bone regenerationU01AR069395 · NIAMS · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI YANG, YUNZHI, ZHOU, XIAOBO · 2016 to 2021
$3.4M
Tissue Engineering Approaches for Improved Treatment of Early Stage Osteonecrosis of the HipR01AR072613 · NIAMS · STANFORD UNIVERSITY · PI GOODMAN, STUART B, YANG, YUNZHI · 2018 to 2022
$2.2M
Vascularization in bone tissue engineering constructsR01AR074458 · NIAMS · STANFORD UNIVERSITY · PI YANG, YUNZHI · 2019 to 2023
$1.7M
Elucidating the role and regulation of periostin in therapy-induced chemoresistance in metastatic breast cancerK01OD022982 · OD · COLORADO STATE UNIVERSITY · PI REGAN, DANIEL PATRICK · 2016 to 2021
$720k
NCATS NIH HHS L30 TR002126NIAMS NIH HHS R01 AR057837NIAMS NIH HHS R01 AR072613NIAMS NIH HHS R01 AR074458NIAMS NIH HHS U01 AR069395NIH HHS K01 OD022982
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

TibiaTissue ScaffoldsAnimalsBone RegenerationPilot ProjectsSheepTissue EngineeringX-Ray Microtomography3D printed scaffoldsin vivo bioreactorlarge bone defectprevascularizationsheep model

Identifiers

PMID33858216
PMCPMC8742287
OpenAlexW3153878524

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.