Evidence map›Paper›PMID 33857485›Full record

ReviewJournal of molecular and cellular cardiology2021

Sarcoplasmic reticulum-mitochondria communication; implications for cardiac arrhythmia.

Shanna Hamilton, Radmila Terentyeva, Richard T Clements, Andriy E Belevych, Dmitry Terentyev

Open access · greenAbstract readReview
In one paragraph

Review in Journal of molecular and cellular cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 37 citations in OpenAlex.

  1. Restoration of mitochondrial CaJournal of molecular and cellular cardiology · 2026
    Article
  2. Article
  3. Increased Intermembrane Space [CaCirculation research · 2025
    Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. Mitochondrial dysfunction as a central hub linking NaFrontiers in cardiovascular medicine · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Citrullination is linked to reduced CaActa physiologica (Oxford, England) · 2022
    Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Shanna HamiltonDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America.
Radmila TerentyevaDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America.
Richard T ClementsBiomedical & Pharmaceutical Sciences, University of Rhode Island, Kingston, RI, United States of America.
Andriy E BelevychDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America.
Dmitry TerentyevDepartment of Physiology and Cell Biology, Davis Heart and Lung Research Institute, Wexner Medical Center, The Ohio State University, Columbus, OH, United States of America. Electronic address: dmitry.terentyev@osumc.edu.
The Ohio State University Wexner Medical Center · USUniversity of Rhode Island · US

Funding

Novel Mechanisms of Regulation of SK channels: Implications for Cardiac ArrhythmiaR01HL142588 · NHLBI · OHIO STATE UNIVERSITY · PI TERENTYEV, DMITRY A · 2019 to 2022
$2.4M
REgulation of Calcium Homeostasis by MyomiRs in Heart FailureR01HL121796 · NHLBI · RHODE ISLAND HOSPITAL · PI TERENTYEV, DMITRY A · 2015 to 2019
$2.0M
Surgical Cardioprotection Through BKCa-Dependent Modulation of Mitochondrial SupercomplexesR01HL135236 · NHLBI · UNIVERSITY OF RHODE ISLAND · PI CLEMENTS, RICHARD T · 2018 to 2021
$1.9M
NHLBI NIH HHS R01 HL121796NHLBI NIH HHS R01 HL135236NHLBI NIH HHS R01 HL142588
6 · The paper itself

Abstract

Sudden cardiac death due to ventricular tachyarrhythmias remains the major cause of mortality in the world. Heart failure, diabetic cardiomyopathy, old age-related cardiac dysfunction and inherited disorders are associated with enhanced propensity to malignant cardiac arrhythmias. Both defective mitochondrial function and abnormal intracellular Ca

Indexed as

BiomarkersDisease SusceptibilitySignal TransductionAnimalsArrhythmias, CardiacCalciumCalcium SignalingEnergy MetabolismHomeostasisHumansMitochondria, HeartMolecular Targeted TherapyOxidation-ReductionSarcoplasmic ReticulumBiomarkersCalciumCalcium signalingCardiac arrhythmiaMitochondriaSarcoplasmic reticulum

Identifiers

PMID33857485
PMCPMC8217367
OpenAlexW3154460101

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.