Evidence map›Paper›PMID 33857136›Full record

ArticlePLoS neglected tropical diseases2021

Deciphering the introduction and transmission of SARS-CoV-2 in the Colombian Amazon Basin.

Nathalia Ballesteros, Marina Muñoz, Luz Helena Patiño, Carolina Hernández, Felipe González-Casabianca, Iván Carroll, Mauricio Santos-Vega, Jaime Cascante, Andrés Angel, Alejandro Feged-Rivadeneira and 15 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

25 authors.

Nathalia BallesterosCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.ORCID 0000-0002-8388-0132
Marina MuñozCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.ORCID 0000-0002-4216-6928
Luz Helena PatiñoCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.
Carolina HernándezCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.
Felipe González-CasabiancaGestión y desarrollo urbanos, Facultad de Estudios Internacionales, Políticos y Urbanos, Universidad del Rosario, Bogotá, Colombia.ORCID 0000-0001-9445-3809
Iván CarrollFacultad de Ingeniería, Universidad de Los Andes, Bogotá, Colombia.ORCID 0000-0002-9310-8664
Mauricio Santos-VegaGrupo de biología matemática y computacional, Departamento de Ingeniería Biomédica, Universidad de los Andes, Bogotá, Colombia.ORCID 0000-0002-8130-6014
Jaime CascanteGrupo de biología matemática y computacional, Departamento de Ingeniería Biomédica, Universidad de los Andes, Bogotá, Colombia.ORCID 0000-0002-3958-6665
Andrés AngelDepartamento de Matemáticas, Universidad de Los Andes, Bogotá, Colombia.ORCID 0000-0002-7210-404X
Alejandro Feged-RivadeneiraGestión y desarrollo urbanos, Facultad de Estudios Internacionales, Políticos y Urbanos, Universidad del Rosario, Bogotá, Colombia.ORCID 0000-0001-8649-4213
Mónica Palma-CueroLaboratorio de Salud Púbica Departamental de Amazonas, Leticia, Colombia.
Carolina FlórezInstituto Nacional de Salud, Bogotá, Colombia.ORCID 0000-0003-4223-2742
Sergio GomezInstituto Nacional de Salud, Bogotá, Colombia.ORCID 0000-0002-1092-9118
Adriana van de GuchteDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0002-0771-3842
Zenab KhanDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Jayeeta DuttaDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0003-1410-3409
Ajay OblaDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0003-4713-3284
Hala Alejel AlshammaryDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Ana S Gonzalez-ReicheDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0003-3583-4497
Matthew M HernandezDepartment of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0001-6217-7264
Emilia Mia SordilloDepartment of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0001-7787-3051
Viviana SimonDepartment of Microbiology, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Harm van BakelDepartment of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0002-1376-6916
Alberto E Paniz-MondolfiDepartment of Pathology, Molecular and Cell Based Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.ORCID 0000-0003-1259-1736
Juan David RamírezCentro de Investigaciones en Microbiología y Biotecnología-UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia.ORCID 0000-0002-1344-9312

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe SARS-CoV-2 pandemic has forced health authorities across the world to take important decisions to curtail its spread. Genomic epidemiology has emerged as a valuable tool to understand introductions and spread of the virus in a specific geographic location. METHODOLOGY/PRINCIPAL

findingsHere, we report the sequences of 59 SARS-CoV-2 samples from inhabitants of the Colombian Amazonas department. The viral genomes were distributed in two robust clusters within the distinct GISAID clades GH and G. Spatial-temporal analyses revealed two independent introductions of SARS-CoV-2 in the region, one around April 1, 2020 associated with a local transmission, and one around April 2, 2020 associated with other South American genomes (Uruguay and Brazil). We also identified ten lineages circulating in the Amazonas department including the P.1 variant of concern (VOC). CONCLUSIONS/SIGNIFICANCE: This study represents the first genomic epidemiology investigation of SARS-CoV-2 in one of the territories with the highest report of indigenous communities of the country. Such findings are essential to decipher viral transmission, inform on global spread and to direct implementation of infection prevention and control measures for these vulnerable populations, especially, due to the recent circulation of one of the variants of concern (P.1) associated with major transmissibility and possible reinfections.

Indexed as

ColombiaCOVID-19HumansIndians, South AmericanSARS-CoV-2Spatial AnalysisTime Factors

Identifiers

PMID33857136
PMCPMC8078805

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.