Evidence map›Paper›PMID 33856891›Full record

ArticleJCO global oncology2021

Consensus on the Treatment and Follow-Up for Metastatic Castration-Resistant Prostate Cancer: A Report From the First Global Prostate Cancer Consensus Conference for Developing Countries (PCCCDC).

Fernando Cotait Maluf, Felipe Moraes Toledo Pereira, Adriano Gonçalves Silva, Aldo Lourenço Abbade Dettino, Ana Paula Garcia Cardoso, André Seeke Sasse, Andrey Soares, Ariel Galapo Kann, Daniel Herchenhorn, Denis Leonardo Fontes Jardim and 13 more

Open access · goldAbstract readConsensus Statement
In one paragraph

Article in JCO global oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 18 citations in OpenAlex.

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  15. Selective ablation of TRA-1-60Theranostics · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 13 institutions in 4 countries.

Fernando Cotait MalufHospital Israelita Albert Einstein, São Paulo, Brazil.ORCID 0000-0001-6122-1374
Felipe Moraes Toledo PereiraLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0003-0986-5812
Adriano Gonçalves SilvaLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0002-5502-8006
Aldo Lourenço Abbade DettinoLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0002-1186-941X
Ana Paula Garcia CardosoHospital Israelita Albert Einstein, São Paulo, Brazil.
André Seeke SasseLatin American Oncology Group (LACOG), Porto Alegre, Brazil.
Andrey SoaresHospital Israelita Albert Einstein, São Paulo, Brazil.ORCID 0000-0003-4980-6729
Ariel Galapo KannLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0002-7260-2030
Daniel HerchenhornLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0001-5166-848X
Denis Leonardo Fontes JardimLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0003-4663-1521
Diego Emilio Lopera CortésClínica Oncólogos del Occidente SAS, Manizales, Colombia.ORCID 0000-0002-3969-9512
Fábio Roberto KaterBeneficência Portuguesa de São Paulo, São Paulo, Brazil.
Igor A Protzner MorbeckLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0002-8833-4261
João Francisco Navarro ReolonBeneficência Portuguesa de São Paulo, São Paulo, Brazil.
José Augusto RinckLatin American Oncology Group (LACOG), Porto Alegre, Brazil.
Juan Jose ZarbáHospital Zenon Santillán, Nacional University of Tucumán, Tucumán, Argentina.
Juan Pablo SadeLatin American Oncology Group (LACOG), Porto Alegre, Brazil.
Karine Martins da TrindadeLatin American Oncology Group (LACOG), Porto Alegre, Brazil.
Leonardo Atem G A CostaLatin American Oncology Group (LACOG), Porto Alegre, Brazil.
Lucas V Dos SantosBeneficência Portuguesa de São Paulo, São Paulo, Brazil.
Manuel Caitano MaiaLatin American Oncology Group (LACOG), Porto Alegre, Brazil.ORCID 0000-0001-9496-8263
Mariana Bruno SiqueiraLatin American Oncology Group (LACOG), Porto Alegre, Brazil.
Silke GillessenOncology Institute of Southern Switzerland (IOSI), Bellinzona and Università della Svizzera Italiana, Lugano, Switzerland.ORCID 0000-0001-5746-6555
Beneficência Portuguesa de São Paulo · BRD’Or Institute for Research and Education · BRHospital Israelita Albert Einstein · BRAC Camargo Hospital · BRAustral University · ARHospital Alemão Oswaldo Cruz · BRHospital Sírio-Libanês · BRInsper · BRInstituto de Oncologia do Paraná · BRInstituto do Sono · BRNational University of Tucumán · ARUniversidade Católica de Brasília · BRUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo present a summary of the recommendations for the treatment and follow-up for metastatic castration-resistant prostate cancer (mCRPC) as acquired through a questionnaire administered to 99 physicians working in the field of prostate cancer in developing countries who attended the Prostate Cancer Consensus Conference for Developing Countries.

methodsA total of 106 questions out of more than 300 questions addressed the use of imaging in staging mCRPC, treatment recommendations across availability and response to prior drug treatments, appropriate drug treatments, and follow-up, and those same scenarios when limited resources needed to be considered. Responses were compiled and the percentages were presented by clinicians to support each response. Most questions had five to seven relevant options for response including abstain and/or unqualified to answer, or in the case of yes or no questions, the option to abstain was offered.

resultsMost of the recommendations from this panel were in line with prior consensus, including the preference of a new antiandrogen for first-line therapy of mCRPC. Important aspects highlighted in the scenario of limited resources included the option of docetaxel as treatment preference as first-line treatment in several scenarios, docetaxel retreatment, consideration for reduced doses of abiraterone, and alternative schedules of an osteoclast-targeted therapy.

conclusionThere was wide-ranging consensus in the treatment for men with mCRPC in both optimal and limited resource settings.

Indexed as

Prostatic Neoplasms, Castration-ResistantAndrogen AntagonistsDeveloping CountriesDocetaxelFollow-Up StudiesHumansMaleAndrogen AntagonistsDocetaxel

Identifiers

PMID33856891
PMCPMC8162971
OpenAlexW3152757016

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.