Evidence map›Paper›PMID 33856512›Full record

ArticlePediatric surgery international2021

Crystallized phenol for treatment of pilonidal sinus disease in children: a comparative clinical study.

Serkan Arslan, Mehmet Hanifi Okur, Erol Basuguy, Bahattin Aydogdu, Hikmet Zeytun, Suat Cal, Serdest Tegin, Mustafa Azizoglu

Registry-linked trialAbstract readClinical StudyComparative Study
PubMed Publisher
In one paragraph

Article in Pediatric surgery international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05404243 (Randomized Clinical Trial to Test the Efficacy and Safety of Phenolization in Uncomplicated Sacrococcygeal Pilonidal Disease), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05404243 phase4completednot on this map

Randomized Clinical Trial to Test the Efficacy and Safety of Phenolization in Uncomplicated Sacrococcygeal Pilonidal Disease

TypeinterventionalSponsorHJ23Ran2021 to 2022Enrolled122ConditionsSacrococcygeal Fistula, Pilonidal Sinus, Pilonidal Disease, Pilonidal Disease of Natal CleftArmsphenolization, Conventional surgery
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Comparative Outcomes of Surgical Techniques for Pilonidal Sinus: A Turkish Retrospective Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  2. Article
  3. Article
  4. Article
  5. Comparison of Phenol Application and Endoscopic Pilonidal Sinus Treatment in Pediatric Pilonidal Sinus Disease.Pediatrics international : official journal of the Japan Pediatric Society
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Serkan ArslanDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey. drserkanarslan@hotmail.com.
Mehmet Hanifi OkurDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey.
Erol BasuguyDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey.
Bahattin AydogduDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey.
Hikmet ZeytunDepartment of Pediatric Surgery, Faculty of Medicine, Gaziantep University, Sahinbey, Turkey.
Suat CalDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey.
Serdest TeginDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey.
Mustafa AzizogluDepartment of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, AZ, 21000, Turkey.
Dicle University · TRGaziantep University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of this study was to present our experience in the use of crystallized phenol (CP) to treat pediatric patients with 'simple' and complex' Pilonidal sinus disease (PSD). MATERIALS AND

methodsPatients who underwent CP treatment in between January 2015 and January 2020 were evaluated retrospectively, using prospectively collected data. The patients were divided into simple and complicated groups. The groups were assigned depending on the number of sinuses and clinical presentation. The groups were compared in terms of age, sex, number of sessions, cost analysis, body mass index (BMI), recurrence, time resolution, cosmetic results, results /improvement, and complications.

resultsThis study included 54 patients: 28 (52%) girls and 26 (48%) boys. The mean number of sinuses was 2.4. Symptoms included discharge in 50 (92%) patients, and pain in 42 (78%) patients. Fifty (93%) patients experienced mild pain during the procedure, whereas four (7%) patients had moderate pain. The mean number of CP sessions was 2.9; mean numbers of CP sessions were 2.2 and 4.2 in the Simple and Complicated groups. In total, 5 of 54 patients (9%) had recurrence.At the end of treatment, therapeutic success was achieved in 49 of 54 (91%) patients: 31 of 33 (94%) patients in the Simple group and 18 of 21 patients (86%) in the complicated group. The mean treatment cost for the whole cohort was $17.40. One patient (2%) presented with moderate skin burns. Cosmesis was deemed acceptable by patients, although there was evidence of minor skin burns following the procedure.

conclusionsThe findings showed that the CP procedure was advantageous for treatment of PSD, because it was minimally invasive, cost-effective, provided good cosmesis, and had a high success rate and low complication rate. Furthermore, it did not require prior examination, and could be performed under local anesthesia. Therefore, the CP procedure may be useful as a first-line treatment option in children with PSD.

Indexed as

AdolescentChildCohort StudiesFemaleHumansMalePhenolPilonidal SinusRecurrenceRetrospective StudiesSclerosing SolutionsTreatment OutcomePhenolSclerosing SolutionsChildrenCrystallizedDiseasePhenolPilonidalSinus

Identifiers

PMID33856512
OpenAlexW3154930146

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.