Evaluating Left Ventricular Systolic Synchronicity with Real-Time 3D Echocardiography in Newborns.

Min Xu, Weidong Ren, Feng Xiong, Shuzhen Wang, Lijuan Zhang, Chunxia Liu, Xiaofeng Huang, Yali Lei

Abstract read

In one paragraph

Article in Pediatric cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors at 3 institutions in 1 country.

Min XuDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China.

Weidong RenDepartment of Ultrasound, Shengjing Hospital of China Medical University, 36# of Sanhao St. Heping District, Shenyang, 110004, Liaoning, China.

Feng XiongDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China. fengxiong1375@163.com.

Shuzhen WangDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China.

Lijuan ZhangDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China.

Chunxia LiuDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China.

Xiaofeng HuangDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China.

Yali LeiDepartment of Cardiac Ultrasound, The Third People's Hospital of Chengdu, The Affiliated Hospital of Southwest Jiaotong University, 82# of Qinglong St. Qingyang District, Chengdu, 610031, Sichuan, China.

Chengdu Third People's Hospital · CNSouthwest Jiaotong University · CNChina Medical University · CN

Funding

Sichuan Project of Science and Technology 2018JY0385

6 · The paper itself

Abstract

Knowing the normal values of left ventricular (LV) systolic synchronicity in the early neonatal period is very important for understanding myocardial function. This retrospective study analyzed data of 105 newborns who were examined using real-time 3-dimensional echocardiography (RT3DE). The time to the point of minimal regional systolic volume (Tmsv) was measured from volume-time curves in each segment. Standard deviation (SD) and maximal difference (Dif) of Tmsv were calculated from 16 (6 basal/6 mid/4 apical), 12 (6 basal/6 mid), and 6 (basal) LV segments with the corresponding parameters adjusted for the R-R interval. Influences of age, sex, gestational age, birth weight, and heart rate on parameters were explored. Data showed no significant difference among Tmsv-16-SD, Tmsv-12-SD, and Tmsv-6-SD. A strong correlation was found between Tmsv-6-SD and Tmsv-6-Dif (r = 0.83, P < 0.001), Tmsv-12-SD and Tmsv-6-SD (r = 0.77, P < 0.001), and Tmsv-12-Dif and Tmsv-6-Dif (r = 0.76, P < 0.001) and a moderate correlation was found between Tmsv-16-SD and Tmsv-16-Dif (r = 0.66, P < 0.001), Tmsv-6-SD and Tmsv-12-Dif (r = 0.62, P < 0.001), and Tmsv-12-SD and Tmsv-6-Dif (r = 0.61, P < 0.001). Heart rate correlated negatively with Tmsv (r = - 0.03 to - 0.11, P < 0.004-0.000), but had no effect on parameters adjusted for %R-R. Age, sex, gestational age, and birth weight did not affect any of these parameters. Tmsv-Dif and Tmsv-SD measured from 16 segments using RT3DE are useful as possible parameters for evaluating LV systolic synchronicity in normal newborns.

Indexed as

Ventricular Function, LeftEchocardiography, Three-DimensionalFemaleHeart RateHeart VentriclesHumansInfant, NewbornMaleReference ValuesRetrospective StudiesNewbornsReal-time three-dimensional echocardiographySystolic synchronicity

Identifiers

PMID33856496

DOI10.1007/s00246-021-02601-5

OpenAlexW3155783824

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.