Evidence map›Paper›PMID 33856321›Full record

ArticleThe western journal of emergency medicine2021

Nobody Wants to Be Narcan'd: A Pilot Qualitative Analysis of Drug Users' Perspectives on Naloxone.

Jeffrey T Lai, Charlotte E Goldfine, Brittany P Chapman, Melissa M Taylor, Rochelle K Rosen, Stephanie P Carreiro, Kavita M Babu

Abstract read
In one paragraph

Article in The western journal of emergency medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Trial
  2. Observational
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  10. Nalbuphine Potentiates Reversal of Fentanyl Overdose by Naloxone.Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  11. Article
  12. Observational
  13. Article
  14. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey T LaiUniversity of Massachusetts Medical School, Department of Emergency Medicine, Worcester, Massachusetts.
Charlotte E GoldfineBrigham and Women's Hospital, Department of Emergency Medicine, Boston, Massachusetts.
Brittany P ChapmanUniversity of Massachusetts Medical School, Department of Emergency Medicine, Worcester, Massachusetts.
Melissa M TaylorUniversity of Massachusetts Medical School, Department of Emergency Medicine, Worcester, Massachusetts.
Rochelle K RosenBrown University School of Public Health, Department of Behavioral and Social Sciences, Providence, Rhode Island.
Stephanie P CarreiroUniversity of Massachusetts Medical School, Department of Emergency Medicine, Worcester, Massachusetts.
Kavita M BabuUniversity of Massachusetts Medical School, Department of Emergency Medicine, Worcester, Massachusetts.

Funding

Sentanyl: Emergency Department-Based Surveillance for Clandestine OpioidsR21DA046734 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BABU, KAVITA M · 2018 to 2019
$507k
NIDA NIH HHS R21 DA046734
6 · The paper itself

Abstract

introductionBystander naloxone distribution is an important component of public health initiatives to decrease opioid-related deaths. While there is evidence supporting naloxone distribution programs, the effects of increasing naloxone availability on the behavior of people who use drugs have not been adequately delineated. In this study we sought to 1) evaluate whether individuals' drug use patterns have changed due to naloxone availability; and 2) explore individuals' knowledge of, access to, experiences with, and perceptions of naloxone.

methodsWe conducted a pilot study of adults presenting to the emergency department whose medical history included non-medical opioid use. Semi-structured interviews were conducted with participants and thematic analysis was used to code and analyze interview transcripts.

resultsTen participants completed the study. All were aware of naloxone by brand name (Narcan) and had been trained in its use, and all but one had either currently or previously possessed a kit. Barriers to naloxone administration included fear of legal repercussions, not having it available, and a desire to avoid interrupting another user's "high." Of the eight participants who reported being revived with naloxone at least once during their lifetime, all described experiencing a noxious physical response and expressed a desire to avoid receiving it again. Furthermore, participants did not report increasing their use of opioids when naloxone was available.

conclusionsParticipants were accepting of and knowledgeable about naloxone, and were willing to administer naloxone to save a life. Participants tended to use opioids more cautiously when naloxone was present due to fears of experiencing precipitated withdrawal. This study provides preliminary evidence countering the unsubstantiated narrative that increased naloxone availability begets more high-risk opioid use and further supports increasing naloxone access.

Indexed as

Opioid-Related DisordersAdultDrug OverdoseDrug UsersEmergency Service, HospitalFemaleHealth Services AccessibilityHumansMaleNaloxoneNarcotic AntagonistsPilot ProjectsNaloxoneNarcotic Antagonists

Identifiers

PMID33856321
PMCPMC7972385

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.