ArticleActa dermato-venereologica2021
Long-term Mortality among Patients with Chronic Ulcers.
Article in Acta dermato-venereologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 3 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Clinical dosimetry and efficacy of LED photobiomodulation for chronic lower-limb wound healing: a systematic review of randomized trials.Lasers in medical science · 2026Pooled it
- Clinical trials on 3D bioprinted scaffolds for lower extremity vascular, diabetic and pressure ulcers: a systematic review.Frontiers in bioengineering and biotechnology · 2026Pooled it
- Qualitative Comparison of LED and LASER Effects on Cutaneous Wound Healing: A Systematic Review of Experimental Studies.Cell biochemistry and function · 2026Pooled it
- Cardiovascular impact of chronic venous disease: A systematic review and meta-analysis.International journal of cardiology. Heart & vasculature · 2026Review
- Malignancy Recorded Among Secondary Diagnoses and In-Hospital Mortality in Patients Hospitalized with Chronic Ulcers: A Nationwide Romanian Patient-Level Cohort Study.Journal of clinical medicine · 2026Article
- Patient Safety in Ulcer Management: Healthcare Professionals' Experiences of Systemic Challenges Across Primary and Secondary Healthcare Settings.Healthcare (Basel, Switzerland) · 2026Article
- Convolutional Neural Networks in Chronic Wound Segmentation and Tissue Classification Using Real-World Images.International wound journal · 2026Article
- Increases in One-year Mortality Risk Among Chronic Skin Ulcer Patients During the Period 1980-2020.Acta dermato-venereologica · 2026Article
- Machine Learning Applications for Venous Ulcer Assessment and Wound Care: A Review.Diagnostics (Basel, Switzerland) · 2026Review
- Hierarchical Delivery of Anti-Inflammatory Compound and Stem Cells for Chronic Wounds.Pharmaceutics · 2025Article
- The Use of Plant-Derived Extracellular Vesicles in Regenerative Medicine Applied to Cutaneous Wound Healing.Pharmaceutics · 2025Review
- Frailty and comorbidity in older adults with and without diabetes and chronic leg ulcer: A cross-sectional study.International wound journal · 2025Article
- Article
- Characteristics of chronic ulcer patients by gender and ulcer aetiology from a multidisciplinary wound centre.International wound journal · 2024Article
- The role of split-thickness skin grafting in the treatment of vasculitic and pyoderma gangrenosum ulcers in a multidisciplinary wound centre.International wound journal · 2024Article
- Oxygen Saturation Increase in Ischemic Wound Tissues after Direct and Indirect Revascularization.Biomedicines · 2024Article
- Hard-to-Heal Wound Healing: Superiority of Hydrogel EHO-85 (ContainingGels (Basel, Switzerland) · 2023Article
- Quality registry improves the data of chronic ulcers: Validation of Tampere Wound Registry.International wound journal · 2023Article
- Antibiotic prescription using a digital decision support system: a register-based study of patients with hard-to-heal ulcers in Sweden.BMJ open · 2022Article
- Superiority of a Novel Multifunctional Amorphous Hydrogel ContainingJournal of clinical medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic ulcers cause a significant burden to patients and society. This study evaluated long-term mortality among patients with chronic ulcers diagnosed at a dermatology clinic between 1980 and 2010. The mortality risk and causes of death of 3,489 patients with ulcers were compared with a matched reference group of 10,399 individuals, and factors associated with increased mortality risk were examined. Long-term mortality was increased in patients with chronic ulcers (hazard ratio (HR) 1.74) and in both males and females (HR 1.99 and 1.62, respectively). Diabetes was the most relevant underlying cause of death (HR 8.98), and of the immediate causes of death, sepsis was strongly associated with mortality (HR 5.86). The mortality risk was highest among those with arterial ulcers (HR 2.85), but also increased in patients with atypical, mixed and venous leg ulcers. In conclusion, patients with chronic ulcers are at an increased mortality risk irrespective of age, sex and ulcer aetiology.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.