Evidence map›Paper›PMID 33855868›Full record

Trial reportFuture oncology (London, England)2021

Health-related quality of life and pain with selinexor in patients with advanced dedifferentiated liposarcoma.

Mrinal Gounder, Albiruni R Abdul Razak, Adrienne M Gilligan, Hoyee Leong, Xiwen Ma, Neeta Somaiah, Sant P Chawla, Javier Martin-Broto, Giovanni Grignani, Scott M Schuetze and 9 more

Open access · hybridAbstract readClinical Trial, Phase IIIMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in Future oncology (London, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Selinexor in Advanced, Metastatic Dedifferentiated Liposarcoma: A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2022
    Trial
  2. Liposarcoma: State of the Art-A Scoping Review.Medical sciences (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 14 institutions in 5 countries.

Mrinal GounderMemorial Sloan Kettering Cancer Center, Weill Cornell Medical College, NY 10021, USA.
Albiruni R Abdul RazakToronto Sarcoma Program, Princess Margaret Cancer Centre, Toronto, ON, M5G 2C1, Canada.
Adrienne M GilliganKaryopharm Therapeutics, Newton, MA 02459, USA.
Hoyee LeongKaryopharm Therapeutics, Newton, MA 02459, USA.
Xiwen MaKaryopharm Therapeutics, Newton, MA 02459, USA.
Neeta SomaiahDepartment of Sarcoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA.
Sant P ChawlaSarcoma Oncology Center, Santa Monica, CA 90403, USA.
Javier Martin-BrotoInstitute of Biomedicine Research (IBIS)/CSIC/Universidad de Sevilla, Virgen del Rocio University Hospital, Calle Antonio Maura Montaner, 41013, Sevilla, Spain.
Giovanni GrignaniDivision of Medical Oncology, Candiolo Cancer Institute, FPO-IRCCS, 10060, Candiolo (TO), Italy.ORCID https://orcid.org/0000-0001-5515-569X
Scott M SchuetzeDivision of Hematology/Oncology, University of Michigan, Ann Arbor, MI 48109, USA.
Bruno VincenziPoliclinico Universitario Campus, Bio-Medico, Via Álvaro del Portillo, 200, 00128, Roma, Italy.
Andrew J WagnerDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.
Bartosz ChmielowskiDivision of Hematology-Oncology, Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, CA 90024, USA.
Robin L JonesThe Royal Marsden NHS Foundation Trust & The Institute of Cancer Research, London, SM2 5PT, UK.
Jatin ShahKaryopharm Therapeutics, Newton, MA 02459, USA.
Sharon ShachamKaryopharm Therapeutics, Newton, MA 02459, USA.
Michael KauffmanKaryopharm Therapeutics, Newton, MA 02459, USA.
Richard F RiedelDepartment of Medicine, Duke University Medical Center, Durham, NC 27710, USA.
Steven AttiaDepartment of Internal Medicine, Division of Hematology/Oncology, Mayo Clinic, Jacksonville, FL 32224, USA.
Karyopharm Therapeutics (United States) · USCampus Bio Medico University Hospital · ITCandiolo Cancer Institute · ITDana-Farber Cancer Institute · USDuke University · USInstituto de Biomedicina de Sevilla · ESMayo Clinic in Florida · USMemorial Sloan Kettering Cancer Center · USPrincess Margaret Cancer Centre · CARoyal Marsden NHS Foundation Trust · GBSarcoma Oncology Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of Michigan · USUSC Norris Comprehensive Cancer Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Karyopharm TherapeuticsNCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Quality of LifeAdultAgedAged, 80 and overCancer PainCross-Over StudiesFemaleHumansHydrazinesLiposarcomaMaleMiddle AgedNeoplasm StagingPlacebosTriazolesHydrazinesPlacebosselinexorTriazolesadvanced liposarcomapainpatient-reported outcomesprogression-free survivalquality of lifeselective inhibitor of nuclear exportselinexor

Identifiers

PMID33855868
PMCPMC9344436
OpenAlexW3156107342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.