ArticleJournal of diabetes2021
Diabetic ketoacidosis drives COVID-19 related hospitalizations in children with type 1 diabetes.
Article in Journal of diabetes, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- Epidemiology and clinical features of SARS-CoV-2 infection in children and adolescents in the pre-Omicron era: A global systematic review and meta-analysis.Journal of global health · 2024Pooled it
- Incidence of diabetic ketoacidosis during COVID-19 pandemic: a meta-analysis of 124,597 children with diabetes.Pediatric research · 2023Pooled it
- Identifying diabetic ketoacidosis encounters at diagnosis among children with type 1 diabetes in claims data.Journal of the Endocrine Society · 2026Article
- Diabetic Ketoacidosis Presenting as Abdominal Pain in a Two-Year-Old Female: A Case Report.Cureus · 2024Article
- Covid 19 and diabetes in children: advances and strategies.Diabetology & metabolic syndrome · 2024Review
- Partnering With Families Through Shared Decision-Making to Increase Connected Pen Use: A Quality Improvement Success Story.Clinical diabetes : a publication of the American Diabetes Association · 2024Article
- Insulin Pump Utilization in 2017-2021 for More Than 22,000 Children and Adults With Type 1 Diabetes: A Multicenter Observational Study.Clinical diabetes : a publication of the American Diabetes Association · 2024Article
- Understanding Providers' Readiness and Attitudes Toward Autoantibody Screening: A Mixed-Methods Study.Clinical diabetes : a publication of the American Diabetes Association · 2024Article
- SARS-CoV-2 vaccination in children and adolescents with and without type 1 diabetes mellitus.Endocrine · 2023Review
- Pediatric COVID-19 and Diabetes: An Investigation into the Intersection of Two Pandemics.Diagnostics (Basel, Switzerland) · 2023Review
- Coronavirus disease 2019 (COVID-19) in pediatric patients with autoimmune disorders.European journal of pediatrics · 2023Review
- Covid-19 infection in children and adolescents and its association with type 1 diabetes mellitus (T1d) presentation and management.Endocrine · 2023Review
- Association Between Health Insurance Type and Adverse Outcomes for Children and Young Adults With Type 1 Diabetes and Coronavirus Disease 2019.Diabetes spectrum : a publication of the American Diabetes Association · 2023Article
- Racial Disparities in Diabetes Technology Adoption and Their Association with HbA1c and Diabetic Ketoacidosis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Real-Time Continuous Glucose Monitoring Reduced Costly Diabetes-Related Events in Adolescents and Young Adults despite Lack of Short-Term Reduction in Hemoglobin A1c.Pediatric diabetes · 2023Article
- Comorbidities increase COVID-19 hospitalization in young people with type 1 diabetes.Pediatric diabetes · 2022Article
- COVID-19 Exacerbates Insulin Resistance During Diabetic Ketoacidosis in Pediatric Patients With Type 1 Diabetes.Diabetes care · 2022Article
- Commentary on CDC data showing an increased risk for pediatric diabetes with COVID-19 infection.Journal of diabetes · 2022Article
- Symptoms and Glycemic Control in Young People With Type 1 Diabetes Following SARS-CoV-2 Infection: An Observational Study.The Journal of clinical endocrinology and metabolism · 2022Observational
- Trends in Type 1 Diabetic Ketoacidosis During COVID-19 Surges at 7 US Centers: Highest Burden on non-Hispanic Black Patients.The Journal of clinical endocrinology and metabolism · 2022Article
Corrections and comments
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Authors and funding
26 authors at 18 institutions in 1 country.
Funding
Abstract
backgroundDiabetes is a risk factor for poor COVID-19 outcomes, but pediatric patients with type 1 diabetes are poorly represented in current studies.
methodsT1D Exchange coordinated a US type 1 diabetes COVID-19 registry. Forty-six diabetes centers submitted pediatric cases for patients with laboratory confirmed COVID-19. Associations between clinical factors and hospitalization were tested with Fisher's Exact Test. Logistic regression was used to calculate odds ratios for hospitalization.
resultsData from 266 patients with previously established type 1 diabetes aged <19 years with COVID-19 were reported. Diabetic ketoacidosis (DKA) was the most common adverse outcome (n = 44, 72% of hospitalized patients). There were four hospitalizations for severe hypoglycemia, three hospitalizations requiring respiratory support (one of whom was intubated and mechanically ventilated), one case of multisystem inflammatory syndrome in children, and 10 patients who were hospitalized for reasons unrelated to COVID-19 or diabetes. Hospitalized patients (n = 61) were more likely than nonhospitalized patients (n = 205) to have minority race/ethnicity (67% vs 39%, P < 0.001), public insurance (64% vs 41%, P < 0.001), higher A1c (11% [97 mmol/mol] vs 8.2% [66 mmol/mol], P < 0.001), and lower insulin pump and lower continuous glucose monitoring use (26% vs 54%, P < 0.001; 39% vs 75%, P < 0.001). Age and gender were not associated with risk of hospitalization. Higher A1c was significantly associated with hospitalization, with an odds ratio of 1.56 (1.34-1.84) after adjusting for age, gender, insurance, and race/ethnicity.
conclusionsHigher A1c remained the only predictor for hospitalization with COVID-19. Diabetic ketoacidosis is the primary concern among this group.
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