Evidence map›Paper›PMID 33855635›Full record

ReviewCurrent oncology reports2021

Update on Histological Reporting Changes in Neuroendocrine Neoplasms.

Konstantin Bräutigam, Antonio Rodriguez-Calero, Corina Kim-Fuchs, Attila Kollár, Roman Trepp, Ilaria Marinoni, Aurel Perren

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current oncology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Konstantin BräutigamInstitute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Antonio Rodriguez-CaleroInstitute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Corina Kim-FuchsDepartment of Visceral Surgery and Medicine, Inselspital Bern University Hospital, University of Bern, Bern, Switzerland.
Attila KollárDepartment of Medical Oncology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Roman TreppDepartment of Diabetes, Endocrinology, Nutritional Medicine and Metabolism, Inselspital, Bern University Hospital and University of Bern, Bern, Switzerland.
Ilaria MarinoniInstitute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland.
Aurel PerrenInstitute of Pathology, University of Bern, Murtenstrasse 31, 3008, Bern, Switzerland. aurel.perren@pathology.unibe.ch.ORCID 0000-0002-6819-6092

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewClassification and nomenclature of neuroendocrine neoplasms (NEN) have frequently changed over the last years. These changes reflect both increasing knowledge and international standardisation. RECENT

findingsThe most recent changes in the Gastro-Entero-Pancreatic system induced the concept of well-differentiated NET with high proliferation rate (NET G3), explaining partially the heterogeneity of G3 NEN. Even if the nomenclature in pulmonary NEN is still different, the terms 'carcinoid' and 'atypical carcinoid' are widely overlapping with NET G1 and NET G2. Molecular data shows an additional heterogeneity both in well-differentiated NET and poorly differentiated NEC. However, no studies are available demonstrating clinical usefulness yet. The heterogeneity of NEN regarding the organ of origin, differentiation and molecular subtypes make development of personalised therapy a challenge needing more international and interdisciplinary collaborations and clinical trials allowing stratification according to biological subgroups.

Indexed as

Biomarkers, TumorEpigenesis, GeneticHumansNeuroendocrine TumorsTranscriptomeBiomarkers, TumorClassificationNENNETNeuroendocrine tumourPathologyReporting

Identifiers

PMID33855635
PMCPMC8046746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.