Evidence map›Paper›PMID 33855271›Full record

ArticleHRB open research2020

The future of genomics in Ireland - focus on genomics for health.

Cathal Seoighe, Adrian P Bracken, Patrick Buckley, Peter Doran, Robert Green, Sandra Healy, David Kavanagh, Elaine Kenny, Mark Lawler, Maeve Lowery and 8 more

Abstract read
In one paragraph

Article in HRB open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Cathal SeoigheNational University of Ireland Galway, Galway, H91 TK33, Ireland.
Adrian P BrackenTrinity College Dublin, Dublin, 2, Ireland.
Patrick BuckleyGenuity Science (Ireland) Ltd., Dublin, D18 K7W4, Ireland.
Peter DoranUniversity College Dublin, Dublin, 4, Ireland.
Robert GreenBrigham Health, Broad Institute, Ariadne Labs, Harvard Medical School, Boston, MA, 02115, USA.
Sandra HealyNational University of Ireland Galway, Galway, H91 TK33, Ireland.
David KavanaghGenuity Science (Ireland) Ltd., Dublin, D18 K7W4, Ireland.
Elaine KennyTrinity College Dublin, Dublin, 2, Ireland.
Mark LawlerQueen's University Belfast, Belfast, Northern Ireland, BT7 1NN, Ireland.
Maeve LoweryTrinity College Dublin, Dublin, 2, Ireland.
Derek MorrisNational University of Ireland Galway, Galway, H91 TK33, Ireland.
Darrin MorrisseyNational Institute for Bioprocessing Research and Training, Blackrock, A94 X099, Ireland.
James J O'ByrneMater Misericordiae University Hospital, Dublin, 7, Ireland.
Denis ShieldsUniversity College Dublin, Dublin, 4, Ireland.
Owen SmithUniversity College Dublin, Dublin, 4, Ireland.
Charles A StewardCongenica, Wellcome Genome Campus, Hinxton, Cambridge, CB10 1DR, UK.ORCID https://orcid.org/0000-0001-8829-5349
Brian SweeneyUniversity College Cork, Cork, T12 YN60, Ireland.
Walter KolchNational University of Ireland Galway, Galway, H91 TK33, Ireland.ORCID https://orcid.org/0000-0001-5777-5016

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomics is revolutionizing biomedical research, medicine and healthcare globally in academic, public and industry sectors alike. Concrete examples around the world show that huge benefits for patients, society and economy can be accrued through effective and responsible genomic research and clinical applications. Unfortunately, Ireland has fallen behind and needs to act now in order to catch up. Here, we identify key issues that have resulted in Ireland lagging behind, describe how genomics can benefit Ireland and its people and outline the measures needed to make genomics work for Ireland and Irish patients. There is now an urgent need for a national genomics strategy that enables an effective, collaborative, responsible, well-regulated, and patient centred environment where genome research and clinical genomics can thrive.  We present eight recommendations that could be the pillars of a national genomics health strategy.

Indexed as

ethics of genome researchgenome researchGenomicshealth-economic assessment of clinical genomicsnational genomics strategypatient involvementprecision/personalized medicinesocietal and economic aspects of genome research

Identifiers

PMID33855271
PMCPMC7993626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.