Evidence map›Paper›PMID 33855158›Full record

ArticleSSM - population health2021

Adverse childhood circumstances and cognitive function in middle-aged and older Chinese adults: Lower level or faster decline?

Zhuoer Lin, Xi Chen

Abstract read
In one paragraph

Article in SSM - population health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Association of Adverse Childhood Experiences and Cognitive Health in Older Adults: Rush Memory and Aging Project.The American journal of geriatric psychiatry. Open science, education, and practice · 2026
    Article
  2. Review
  3. Place of Birth and Cognitive Function Among Older Americans: Findings From the Harmonized Cognitive Assessment Protocol.The journals of gerontology. Series B, Psychological sciences and social sciences · 2024
    Article
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Zhuoer LinDepartment of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA.
Xi ChenDepartment of Health Policy and Management, Yale School of Public Health, New Haven, CT, USA.

Funding

Yale Study Support Suite (YES3): Dashboard and Web Portal Software Supporting Research Workflow through integrated, customizable REDCap External ModulesP30AG021342 · NIA · YALE UNIVERSITY · PI Lauren Ferrante · 2002 to 2026
$37.9M
Social Pension, Health, and Healthy AgingK01AG053408 · NIA · YALE UNIVERSITY · PI CHEN, XI · 2018 to 2021
$514k
Old-Age Pension, Household Behavior Change and the Well-being of the EderlyR03AG048920 · NIA · YALE UNIVERSITY · PI CHEN, XI · 2014 to 2015
$328k
NIA NIH HHS K01 AG053408NIA NIH HHS P30 AG021342NIA NIH HHS R03 AG048920
6 · The paper itself

Abstract

We examine the long-term relationship between childhood circumstances and cognitive aging. In particular, we differentiate the level of cognitive deficit from the rate of cognitive decline. Applying a linear mixed-effect model to three waves of China Health and Retirement Longitudinal Surveys (CHARLS 2011, 2013, 2015) and matching cognitive outcomes to CHARLS Life History Survey (2014), we find that key domains of childhood circumstances, including family socioeconomic status (SES), neighborhood cohesion, friendship, and health conditions, are significantly associated with both the level of cognitive deficit and the rate of decline. In contrast, childhood neighborhood safety only affects the level of cognitive deficit. Childhood relationship with mother only affects the rate of cognitive decline. The effects of adverse childhood circumstances are generally larger on level of cognitive deficit than on rate of cognitive decline. Moreover, education plays a more important role in mediating the relationships compared to other later-life factors. These findings suggest that exposure to disadvantaged childhood circumstances can exacerbate cognitive deficit as well as cognitive decline over time, which may be partially ameliorated by educational attainment.

Indexed as

Childhood circumstancesCognitive agingEducationLife course factors

Identifiers

PMID33855158
PMCPMC8025052

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.