ArticleFrontiers in cell and developmental biology2021
Transcriptome Profiling of the Ovarian Cells at the Single-Cell Resolution in Adult Asian Seabass.
Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Single-Cell RNA-Seq of Pituitary and Ovary Identifies Regulators of Reproduction in Yellow Catfish (Animals : an open access journal from MDPI · 2026Article
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- Characterizing the Ovarian Cytogenetic Dynamics of Sichuan Bream (International journal of molecular sciences · 2025Article
- A Single-Cell Atlas of Crab Ovary Provides New Insights Into Oogenesis in Crustaceans.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Single-Nucleus RNA Sequencing Reveals the Transcriptome Profiling of Ovarian Cells in AdolescentAnimals : an open access journal from MDPI · 2024Article
- Characterization of Two Gonadal Genes, zar1 and wt1b, in Hermaphroditic Fish Asian Seabass (Animals : an open access journal from MDPI · 2024Article
- Dynamic changes in cellular atlases and communication patterns within yak ovaries across diverse reproductive states unveiled by single-cell analysis.Frontiers in cell and developmental biology · 2024Article
- Single cell genomics as a transformative approach for aquaculture research and innovation.Reviews in aquaculture · 2023Review
- Single-Cell Atlas Reveals the Hemocyte Subpopulations and Stress Responses in Asian Giant Softshell Turtle during Hibernation.Biology · 2023Article
- Single-Cell Transcriptomics Analysis Reveals a Cell Atlas and Cell Communication in Yak Ovary.International journal of molecular sciences · 2023Article
- Article
- Characterization of the In Vitro Cultured Ovarian Cells in the Asian Yellow Pond Turtle (Biology · 2022Article
- Single-Cell Atlas of the Chinese Tongue SoleFrontiers in cell and developmental biology · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Single-cell RNA sequencing (scRNA-seq) is widely adopted for identifying the signature molecular markers or regulators in cells, as this would benefit defining or isolating various types of cells. Likewise, the signature transcriptome profile analysis at the single cell level would well illustrate the key regulators or networks involved in gametogenesis and gonad development in animals; however, there is limited scRNA-seq analysis on gonadal cells in lower vertebrates, especially in the sexual reversal fish species. In this study, we analyzed the molecular signature of several distinct cell populations of Asian seabass adult ovaries through scRNA-seq. We identified five cell types and also successfully validated some specific genes of germ cells and granulosa cells. Likewise, we found some key pathways involved in ovarian development that may concert germline-somatic interactions. Moreover, we compared the transcriptomic profiles across fruit fly, mammals, and fish, and thus uncovered the conservation and divergence in molecular mechanisms that might drive ovarian development. Our results provide a basis for studying the crucial features of germ cells and somatic cells, which will benefit the understandings of the molecular mechanisms behind gametogenesis and gonad development in fish.
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