Evidence map›Paper›PMID 33854770›Full record

ArticleAnnals of medicine and surgery (2012)2021

The impact of thyroid tumor features on lymph node metastasis in papillary thyroid carcinoma patients in head and neck department at KAMC: A retrospective cross-sectional study.

Amjad O Aljohani, Reyan H Merdad, Anas I Alserif, Layan S Alhemayed, Noor Z Farsi, Thamer A Alsufyani, Haddad H Alkaf, Ameen Z Alherabi, Sherif K Abdelmonim, Mohammad A Alessa

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Influence of S100A2 in Human Diseases.Diagnostics (Basel, Switzerland) · 2022
    Review
  5. Article
  6. Low Expression of miR-491-3p Is Correlated with Lymph Node Metastasis in Gastric Cancer.Evidence-based complementary and alternative medicine : eCAM · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 2 countries.

Amjad O AljohaniAl-Farabi Private College for Dentistry and Nursing, Jeddah, Saudi Arabia.
Reyan H MerdadCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, Saudi Arabia.
Anas I AlserifFaculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Layan S AlhemayedUmm Al-Qura University, Makkah, Saudi Arabia.
Noor Z FarsiUmm Al-Qura University, Makkah, Saudi Arabia.
Thamer A AlsufyaniTaif University, Taif, Saudi Arabia.
Haddad H AlkafDepartment of Head and Neck Surgery, Head and Neck and Skull Base Health Center, King Abdullah Medical City, Makkah, Saudi Arabia.
Ameen Z AlherabiDepartment of Otolaryngology-Head & Neck Surgery, College of Medicine, Umm Al-Qura University, Saudi Arabia.
Sherif K AbdelmonimDepartment of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Ain Shams University, Cairo, Egypt.
Mohammad A AlessaDepartment of Head and Neck Surgery, Head and Neck and Skull Base Health Center, King Abdullah Medical City, Makkah, Saudi Arabia.
Umm al-Qura University · SAKing Abdullah Medical City · SAAin Shams University · EGAl-Farabi College · SAKing Abdulaziz University · SAKing Saud bin Abdulaziz University for Health Sciences · SATaif University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillary thyroid carcinoma (PTC) is the most prevalent type of thyroid cancer. It is one of the most common types of malignancy of the thyroid that spreads to cervical lymph nodes. Lymph node metastasis (LNM) is an important factor when determining recurrence risk, and determining the extent of lymph node involvement can guide treatment. Our main objective is to evaluate the association between the size of the tumor and the number of lymph node metastases in patients with PTC.

methodsWe conducted an electronic retrospective chart review of 125 patients with PTC followed in the Head and Neck Department at KAMC from 2009 to 2020. Twenty-two patients included in our study were pathologically and clinically diagnosed and confirmed to have LNM of PTC.

resultsThe study included 22 PTC patients who had undergone lymph node dissections. Patients had a median age of 38.8 years (IQR = 32.2-54.5), and the median tumor size was 20.5 mm. The most commonly affected level of the neck was IV (76.2%). Distant metastasis M1 was seen in only two patients (9.1%). Tumors sizes >30mm (75%) had ≥5 LNM. Most cases were the classic subtype PTC. For the site of the tumor, the site had a significant impact on the number of LNM (p = 0.004). Multifocality had a high impact on LNM (p = 0.019).

conclusionsThis study showed no association between the size of PTC and the number of LNMs. The bilaterality of PTC was significantly associated with a high number of LNMs.

Indexed as

Lymph node metastasisNeck dissectionPapillary thyroid carcinomaThyroid cancerThyroid in Saudi Arabia

Identifiers

PMID33854770
PMCPMC8027685
OpenAlexW3138828302

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.