Evidence map›Paper›PMID 33854657›Full record

ArticleJournal of clinical medicine research2021

Perioperative Antibiotic Prophylaxis: An Educative Intervention Significantly Increases Compliance.

Eirini Chrysovalantou Martzivanou, Kyriakos Psarras, Panagiotis Monioudis, Kyriakos Vamvakis, Christina Nikolaidou, Georgios Geropoulos, Efstathios T Pavlidis, Nikolaos Symeonidis, Theodoros E Pavlidis

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In one paragraph

Article in Journal of clinical medicine research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Eirini Chrysovalantou MartzivanouSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Kyriakos PsarrasSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Panagiotis MonioudisSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Kyriakos VamvakisDirectorate of Public Health, Prefecture of Kavala, Kavala, Greece.
Christina NikolaidouSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Georgios GeropoulosThoracic Surgery Department, University College London Hospitals, NHS Foundation Trust, London, UK.
Efstathios T PavlidisSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Nikolaos SymeonidisSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Theodoros E PavlidisSecond Surgical Propedeutic Department, Hippocration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Hippocration General Hospital · GRAristotle University of Thessaloniki · GRTechnological Educational Institute of Eastern Macedonia and Thrace · GRUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundImplementation of guidelines in daily clinical practice is often suboptimal, mainly due to doctors' poor compliance with them. Perioperative antibiotic prophylaxis (PAP) is many times administered in patients undergoing elective surgery without proper indication or for longer time than needed. Aim of this study is to investigate the effect of a simple intervention on the compliance of the medical staff with the American Society of Health-System Pharmacists (ASHP) guidelines concerning PAP administration.

methodsA prospective 3-month audit took place including routine surgical procedures (laparoscopic cholecystectomy, inguinal hernia repair and thyroidectomy). An intervention aiming to educate the medical staff was implemented. The intervention included the demonstration of a poster and the training of the medical staff over the guidelines. A re-audit recorded the changes in daily clinical practice.

resultsThe compliance rate regarding the number of PAP doses significantly increased from 0% before the intervention to 68.8% after the intervention for hernia repair and to 53.1% for laparoscopic cholecystectomy. The adherence rate in thyroidectomies increased from 25% to 50%, but without statistical significance. No significant difference was found for other parameters of PAP administration, namely the type of antibiotic used and the timing of the dose administration. Regarding secondary outcomes, hospitalization days were reduced, and cost of antibiotics was significantly decreased (P < 0.05).

conclusionsA simple intervention intending to educate the medical staff was successful in achieving significant improvement on the compliance rate with the PAP guidelines, highlighting the importance of promoting adherence to the already existing, well-established guidelines.

Indexed as

Antibiotic prophylaxisComplianceInterventionSurgical site infection

Identifiers

PMID33854657
PMCPMC8016525
OpenAlexW3138726122

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.