Evidence map›Paper›PMID 33854544›Full record

ReviewNeural plasticity2021

Molecular Factors Mediating Neural Cell Plasticity Changes in Dementia Brain Diseases.

Wojciech Kozubski, Kevin Ong, Wioletta Waleszczyk, Matthew Zabel, Jolanta Dorszewska

Abstract readReview
In one paragraph

Review in Neural plasticity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Mechanisms of cognitive impairment associated with cerebral infarction.Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2024
    Review
  5. Review
  6. Review
  7. Journal of ginseng research · 2023
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wojciech KozubskiChair and Department of Neurology, Poznan University of Medical Sciences, Poland.ORCID 0000-0003-2777-261X
Kevin OngGeneral Medicine Department, Armadale Health Service, Mount Nasura, Australia.ORCID 0000-0001-6204-0989
Wioletta WaleszczykLaboratory of Visual Neurobiology, Department of Neurophysiology, Nencki Institute of Experimental Biology, PAS, Warsaw, Poland.ORCID 0000-0002-7300-6193
Matthew ZabelCollege of Medicine, California Northstate University, CA, USA.ORCID 0000-0003-2591-7379
Jolanta DorszewskaLaboratory of Neurobiology, Department of Neurology, Poznan University of Medical Sciences, Poznan, Poland.ORCID 0000-0002-8241-0403

Funding

Traning Clinical Scientists in Radiological ImagingT32EB005970 · NIBIB · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Eric Y Chang, Rebecca Ann Rakow-Penner · 2007 to 2026
$3.2M
NIBIB NIH HHS T32 EB005970
6 · The paper itself

Abstract

Neural plasticity-the ability to alter a neuronal response to environmental stimuli-is an important factor in learning and memory. Short-term synaptic plasticity and long-term synaptic plasticity, including long-term potentiation and long-term depression, are the most-characterized models of learning and memory at the molecular and cellular level. These processes are often disrupted by neurodegeneration-induced dementias. Alzheimer's disease (AD) accounts for 50% of cases of dementia. Vascular dementia (VaD), Parkinson's disease dementia (PDD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD) constitute much of the remaining cases. While vascular lesions are the principal cause of VaD, neurodegenerative processes have been established as etiological agents of many dementia diseases. Chief among such processes is the deposition of pathological protein aggregates

Indexed as

alpha-SynucleinAlzheimer DiseaseAmyloid beta-PeptidesBiomarkersBrain DiseasesDementiaHumansLewy Body DiseaseNeuronal PlasticityNeuronstau Proteinsalpha-SynucleinAmyloid beta-PeptidesBiomarkersMAPT protein, humantau Proteins

Identifiers

PMID33854544
PMCPMC8021472

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.