Evidence map›Paper›PMID 33854515›Full record

ReviewFrontiers in immunology2021

Case Report: Symptomatic Chronic Granulomatous Disease in the Newborn.

Milica Miladinovic, Boris Wittekindt, Sebastian Fischer, Elise Gradhand, Steffen Kunzmann, Stefanie Y Zimmermann, Shahrzad Bakhtiar, Thomas Klingebiel, Rolf Schlösser, Thomas Lehrnbecher

Open access · goldAbstract readCase ReportsReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. [Chest computed tomography manifestations in neonates with chronic granulomatous disease].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Milica MiladinovicHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
Boris WittekindtHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
Sebastian FischerInstitute of Pathology, University Hospital of Frankfurt, Frankfurt, Germany.
Elise GradhandDepartment of Diagnostic and Interventional Radiology, University Hospital of Frankfurt, Frankfurt, Germany.
Steffen KunzmannClinic of Neonatology and Pediatric Intensive Care, Bürgerhospital, Frankfurt, Germany.
Stefanie Y ZimmermannHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
Shahrzad BakhtiarHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
Thomas KlingebielHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
Rolf SchlösserHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
Thomas LehrnbecherHospital for Children and Adolescents, University Hospital of Frankfurt, Frankfurt, Germany.
University Hospital Frankfurt · DEGoethe University Frankfurt · DEBürgerhospital Frankfurt am Main · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic granulomatous disease (CGD) is a primary immunodeficiency, which is diagnosed in most patients between one and three years of age. Here we report on a boy who presented at birth with extensive skin lesions and lymphadenopathy which were caused by CGD. An analysis of the literature revealed 24 patients with CGD who became symptomatic during the first six weeks of life. Although pulmonary complications and skin lesions due to infection were the leading symptoms, clinical features were extremely heterogenous. As follow-up was not well specified in most patients, the long-term prognosis of children with very early onset of CGD remains unknown.

Indexed as

Age of OnsetBiomarkersBiopsyDiagnosis, DifferentialGranulomatous Disease, ChronicHumansImmunohistochemistryInfant, NewbornLymphadenopathySkin DiseasesTomography, X-Ray ComputedBiomarkerschronic granulomatous diseaseearly onsetneonateoutcomesymptoms

Identifiers

PMID33854515
PMCPMC8039294
OpenAlexW3144986543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.