Evidence map›Paper›PMID 33854506›Full record

ReviewFrontiers in immunology2021

Age-Related Dynamics of Lung-Resident Memory CD8

Nick P Goplen, In Su Cheon, Jie Sun

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. The ageing immune system and its battle with viruses.The Journal of general virology · 2026
    Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. Article
  8. CD4Frontiers in immunology · 2025
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Antigen non-specific CD8bioRxiv : the preprint server for biology · 2024
    Article
  14. Review
  15. Article
  16. Targeting chronic COVID-19 lung injury; Tofacitinib can be used against tissue-resident memory T cells.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2022
    Article
  17. Review
  18. Review
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Nick P GoplenDivision of Pulmonary and Critical Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, United States.
In Su CheonDivision of Pulmonary and Critical Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, United States.
Jie SunDivision of Pulmonary and Critical Medicine, Department of Medicine, Mayo Clinic, Rochester, MN, United States.
Mayo Clinic · US

Funding

Host cellular network governing the development of post SARS-CoV-2 tissue sequelaeR01AI147394 · NIAID · UNIVERSITY OF VIRGINIA · PI Jie Sun · 2020 to 2026
$4.7M
Molecular regulation of protective CD8 immunity against influenza infectionR01AI112844 · NIAID · UNIVERSITY OF VIRGINIA · PI SUN, JIE · 2015 to 2024
$4.5M
Elucidating the roles of alveolar macrophage inflammation and selfrenewal during influenza infectionR01AG069264 · NIA · UNIVERSITY OF VIRGINIA · PI Jie Sun · 2020 to 2026
$3.5M
Roles of tissue-resident helper T cells in mucosal immunity against influenzainfectionR01AI154598 · NIAID · UNIVERSITY OF VIRGINIA · PI SUN, JIE · 2020 to 2024
$2.9M
Simultaneously boosting both humoral and cellular immunity following vaccinationR01AG047156 · NIA · MAYO CLINIC ROCHESTER · PI SUN, JIE · 2015 to 2019
$1.6M
NIAID NIH HHS R01 AI112844NIAID NIH HHS R01 AI147394NIAID NIH HHS R01 AI154598NIA NIH HHS R01 AG047156NIA NIH HHS R01 AG069264
6 · The paper itself

Abstract

Following respiratory viral infections or local immunizations, lung resident-memory T cells (T

Indexed as

Immunologic MemoryAge FactorsAnimalsBiomarkersCD8-Positive T-LymphocytesCOVID-19Disease ResistanceHomeostasisHost-Pathogen InteractionsHumansImmunophenotypingLungLymphocyte CountPulmonary FibrosisSARS-CoV-2T-Lymphocyte SubsetsBiomarkersagehomeostasisinfluenzapathologyresident memoryviral pneumonia

Identifiers

PMID33854506
PMCPMC8039372
OpenAlexW3141775221

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.