Evidence map›Paper›PMID 33854501›Full record

ArticleFrontiers in immunology2021

Integrin Activation Enables Sensitive Detection of Functional CD4

Anna Schöllhorn, Juliane Schuhmacher, Luciana Besedovsky, Rolf Fendel, Anja T R Jensen, Stefan Stevanović, Tanja Lange, Hans-Georg Rammensee, Jan Born, Cécile Gouttefangeas and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Staining of activated ßFrontiers in immunology · 2022
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 2 countries.

Anna SchöllhornDepartment of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
Juliane SchuhmacherDepartment of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
Luciana BesedovskyInstitute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany.
Rolf FendelInstitute of Tropical Medicine, University of Tübingen, Tübingen, Germany.
Anja T R JensenDepartment of Immunology and Microbiology, University of Copenhagen, Copenhagen, Denmark.
Stefan StevanovićDepartment of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
Tanja LangeDepartment of Rheumatology and Clinical Immunology, University of Lübeck, Lübeck, Germany.
Hans-Georg RammenseeDepartment of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
Jan BornInstitute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany.
Cécile GouttefangeasDepartment of Immunology, Institute for Cell Biology, University of Tübingen, Tübingen, Germany.
Stoyan DimitrovInstitute of Medical Psychology and Behavioral Neurobiology, University of Tübingen, Tübingen, Germany.
University of Tübingen · DEGerman Cancer Research Center · DEHeinrich Heine University Düsseldorf · DEUniversity of Copenhagen · DKUniversity of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We have previously shown that conformational change in the β

Indexed as

AdultAgedAmino Acid SequenceBinding SitesCarrier ProteinsCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCOVID-19CytokinesCytomegalovirusEpitopes, T-LymphocyteFemaleHLA AntigensHost-Pathogen InteractionsHumansImmunohistochemistryCarrier ProteinsCytokinesEpitopes, T-LymphocyteHLA AntigensICAM1 protein, humanIntegrinsIntercellular Adhesion Molecule-1antigen specificityCD4+ T cellsCD8+ T cellsintegrin activationSARS-CoV-2

Identifiers

PMID33854501
PMCPMC8040333
OpenAlexW3149022311

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.