Evidence map›Paper›PMID 33854470›Full record

ArticleFrontiers in neurology2021

Pilot Study on Quantitative Cervical Cord and Muscular MRI in Spinal Muscular Atrophy: Promising Biomarkers of Disease Evolution and Treatment?

Giovanni Savini, Carlo Asteggiano, Matteo Paoletti, Stefano Parravicini, Elena Pezzotti, Francesca Solazzo, Shaun I Muzic, Francesco Santini, Xeni Deligianni, Alice Gardani and 7 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
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  7. Review
  8. Muscle quantitative MRI in adult SMA patients on nusinersen treatment: a longitudinal study.Acta myologica : myopathies and cardiomyopathies : official journal of the Mediterranean Society of Myology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 4 countries.

Giovanni SaviniAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Carlo AsteggianoAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Matteo PaolettiAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Stefano ParraviciniDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Elena PezzottiDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Francesca SolazzoAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Shaun I MuzicDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Francesco SantiniDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland.
Xeni DeligianniDepartment of Radiology, Division of Radiological Physics, University Hospital Basel, Basel, Switzerland.
Alice GardaniChild Neuropsychiatry Unit, IRCCS Mondino Foundation, Pavia, Italy.
Giancarlo GermaniAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Lisa M FarinaAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Niels BergslandBuffalo Neuroimaging Analysis Center, Department of Neurology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Claudia A M Gandini Wheeler-KingshottDepartment of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.
Angela BerardinelliChild Neuropsychiatry Unit, IRCCS Mondino Foundation, Pavia, Italy.
Stefano BastianelloAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
Anna PichiecchioAdvanced Imaging and Radiomics Center, Neuroradiology Department, IRCCS Mondino Foundation, Pavia, Italy.
University of Pavia · ITUniversity Hospital of Basel · CHDon Carlo Gnocchi Foundation · ITUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

motor neuron degenerationmuscle fat fractionmuscle MRInusinersen (spinraza)quantitative magnetic resonance imagingspinal cord atrophy and degenerationspinal muscular atrophytreatment monitoring

Identifiers

PMID33854470
PMCPMC8039452
OpenAlexW3150267725

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.