ArticleNature communications2021
TIM4 expression by dendritic cells mediates uptake of tumor-associated antigens and anti-tumor responses.
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Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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0cells of the map it votes in
39citing papers in PubMed
4.4field-weighted citation impact, top 4% of its field
What it found
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Who cites it
39 citing papers in PubMed, 68 citations in OpenAlex.
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- Infiltration of TIM4-positive intratumoral macrophages serves as an adverse prognostic factor in breast cancer.Breast cancer (Tokyo, Japan) · 2026Article
- Dendritic cells: the central partner for cancer immunity.Oncoimmunology · 2025Review
- Mitochondrial-targeted photodynamic therapy combined with TGF-β inhibition potentiates anti-PD-1 therapy in pancreatic ductal adenocarcinoma.Journal of nanobiotechnology · 2025Article
- Coagulation proteases modulate nucleic acid uptake and cGAS-STING-IFN induction in the tumor microenvironment.JCI insight · 2025Article
- Boosting Dendritic Cell Function in Cancer.Cancer medicine · 2025Review
- Lipid nanoparticles as a tool to dissect dendritic cell maturation pathways.Cell reports · 2025Article
- Heterogeneity of Lung Phagocytes and Clearance of Apoptotic Cells in Lung Injury and Repair.Seminars in respiratory and critical care medicine · 2025Review
- A Novel Polymersome Nanocarrier Promotes Anti-Tumour Immunity by Improved Priming of CD8Immunology · 2025Article
- Dendritic cell maturation in cancer.Nature reviews. Cancer · 2025Review
- Cross-priming in cancer immunology and immunotherapy.Nature reviews. Cancer · 2025Review
- Tissue-specific properties of type 1 dendritic cells in lung cancer: implications for immunotherapy.Journal for immunotherapy of cancer · 2025Review
- In-silico pharmacological insights into the therapeutic potential of microRNAs for microplastic-associated cancers.Frontiers in cell and developmental biology · 2025Review
- Article
- Dendritic cell-related hub genes in head-and-neck squamous cell carcinoma: implications for prognosis and immunotherapy.Translational cancer research · 2024Article
- Dendritic Cells in Shaping Anti-Tumor T Cell Response.Cancers · 2024Review
- MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C.iScience · 2024Article
- Dendritic cells as orchestrators of anticancer immunity and immunotherapy.Nature reviews. Clinical oncology · 2024Review
- Dendritic cell-targeted therapy expands CD8 T cell responses to bona-fide neoantigens in lung tumors.Nature communications · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 11 institutions in 6 countries.
Nicoletta Caronni *Department of Cellular Immunology, International Centre for Genetic Engineering and Biotechnology, ICGEB, Trieste, Italy. caronni.nicoletta@hrs.it.
Giulia Maria Piperno *Department of Cellular Immunology, International Centre for Genetic Engineering and Biotechnology, ICGEB, Trieste, Italy.
Francesca SimoncelloDepartment of Cellular Immunology, International Centre for Genetic Engineering and Biotechnology, ICGEB, Trieste, Italy.
Oriana RomanoDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-3483-1115
Simone VodretCardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
Yuichi YanagihashiLaboratory of Biochemistry & Immunology, World Premier International Research Center, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.
Regine DressSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0001-8785-5471
Charles-Antoine DutertreSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.
Mattia BugattiDepartment of Molecular and Translational Medicine, School of Medicine, University of Brescia, Brescia, Italy.
Pierre BourdeleyCentre for Inflammation Biology and Cancer Immunology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Annalisa Del PreteDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID 0000-0002-3738-412X
Tiziana SchioppaDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.ORCID 0000-0002-6303-6065
Emilia Maria Cristina MazzaDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0003-2424-3640
Licio CollavinDepartment of Life Sciences (DSV), University of Trieste, Trieste, Italy.
Serena ZacchignaCardiovascular Biology Laboratory, International Centre for Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.ORCID 0000-0001-6705-3076
Renato OstuniSan Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0003-0460-3426
Pierre GuermonprezCentre for Inflammation Biology and Cancer Immunology, School of Immunology and Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.ORCID 0000-0001-5621-2262
William VermiDepartment of Molecular and Translational Medicine, School of Medicine, University of Brescia, Brescia, Italy.ORCID 0000-0002-2291-2997
Florent GinhouxSingapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.ORCID 0000-0002-2857-7755
Silvio BicciatoDepartment of Life Sciences, University of Modena and Reggio Emilia, Modena, Italy.ORCID 0000-0002-1944-7078
Shigekatzu NagataLaboratory of Biochemistry & Immunology, World Premier International Research Center, Immunology Frontier Research Center, Osaka University, Suita, Osaka, Japan.ORCID 0000-0001-9758-8426
Federica BenvenutiDepartment of Cellular Immunology, International Centre for Genetic Engineering and Biotechnology, ICGEB, Trieste, Italy. benvenuti@icgeb.org.
International Centre for Genetic Engineering and Biotechnology · ITAgency for Science, Technology and Research · SGUniversity of Modena and Reggio Emilia · ITHumanitas University · ITKing's College London · GBOsaka International University · JPUniversity of Trieste · ITThe San Raffaele Telethon Institute for Gene Therapy · ITUniversity of Brescia · ITVita-Salute San Raffaele University · ITWashington University in St. Louis · US
Funding
Cancer Research UK 22369
Abstract
Acquisition of cell-associated tumor antigens by type 1 dendritic cells (cDC1) is essential to induce and sustain tumor specific CD8
Indexed as
AdenocarcinomaAnimalsAntigens, NeoplasmCD8-Positive T-LymphocytesCross-PrimingDendritic CellsHumansImmunologic SurveillanceLungLung NeoplasmsMembrane ProteinsMiceAntigens, NeoplasmMembrane ProteinsTIM-4 protein, mouse
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.