ArticleLight, science & applications2021
Engineering single-molecule fluorescence with asymmetric nano-antennas.
Article in Light, science & applications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Asymmetric Sulfhydryl-Substituted Squaraine Fluorophores for Sustained SIM Imaging in Live Cells.Journal of the American Chemical Society · 2026Article
- Alternative Plasmonic Materials for Fluorescence Enhancement.The journal of physical chemistry. C, Nanomaterials and interfaces · 2024Article
- Surface plasmon polariton-enhanced upconversion luminescence for biosensing applications.Nanophotonics (Berlin, Germany) · 2024Article
- Extended BODIPYs as Red-NIR Laser Radiation Sources with Emission from 610 nm to 750 nm.Molecules (Basel, Switzerland) · 2023Article
- Near-Infrared Light-Activated Oxygen Generator a Multidynamic Photo-Nanoplatform for Effective Anti-Cutaneous Squamous Cell Carcinoma Treatment.International journal of nanomedicine · 2022Article
- Pronounced Linewidth Narrowing of Vertical Metallic Split-Ring Resonators via Strong Coupling with Metal Surface.Nanomaterials (Basel, Switzerland) · 2021Article
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Authors and funding
11 authors.
Funding
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Abstract
As a powerful tool for studying molecular dynamics in bioscience, single-molecule fluorescence detection provides dynamical information buried in ensemble experiments. Fluorescence in the near-infrared (NIR) is particularly useful because it offers higher signal-to-noise ratio and increased penetration depth in tissue compared with visible fluorescence. The low quantum yield of most NIR fluorophores, however, makes the detection of single-molecule fluorescence difficult. Here, we use asymmetric plasmonic nano-antenna to enhance the fluorescence intensity of AIEE1000, a typical NIR dye, by a factor up to 405. The asymmetric nano-antenna achieve such an enhancement mainly by increasing the quantum yield (to ~80%) rather than the local field, which degrades the molecules' photostability. Our coupled-mode-theory analysis reveals that the enhancements stem from resonance-matching between antenna and molecule and, more importantly, from optimizing the coupling between the near- and far-field modes with designer asymmetric structures. Our work provides a universal scheme for engineering single-molecule fluorescence in the near-infrared regime.
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Registered trials
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