Evidence map›Paper›PMID 33853526›Full record

ArticleBMC anesthesiology2021

Development and validation of a 3D printed antiviral ventilator filter - a comparative study.

Ruth Shaylor, Mathew Francis, Esther Shaylor, Solomon Dadia, Barak Cohen

Abstract readComparative Study
In one paragraph

Article in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ruth ShaylorDivision of Anesthesia, Intensive Care, and Pain Management, Tel-Aviv Medical Center; Tel-Aviv University, 6 Weizmann Street, 6423906, Tel-Aviv, Israel.
Mathew FrancisDepartment of Food Science, University of Leeds, Leeds, UK.
Esther ShaylorSupply Division, United Nations Children's Fund, Copenhagen, Denmark.
Solomon DadiaSurgical 3D printing Laboratory, Tel-Aviv Medical Center, Tel-Aviv, Israel.
Barak CohenDivision of Anesthesia, Intensive Care, and Pain Management, Tel-Aviv Medical Center; Tel-Aviv University, 6 Weizmann Street, 6423906, Tel-Aviv, Israel. BarakC@tlvmc.gov.il.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe current coronavirus infectious disease 2019 (COVID-19) pandemic has caused unexpected pressure on medical supplies, interrupting supply chains and increasing prices. The supply of antiviral filters which form an essential part of the ventilator circuit have been affected by these issues. Three-dimensional (3D) printing may provide a solution to some of these issues.

methodsWe designed and tested 3D printed heat and moisture exchange (HME) and antiviral casing. For each casing we tested two different filter materials derived from a sediment water filter cartridge or 1.5-μm glass fiber filter paper. A polyurethane sponge was used for the HME. Each design was tested for circuit leak, circuit compliance, peak inspiratory pressure and casing integrity using methylene blue dye.

resultsWe designed, produced, and tested two different types of antiviral filters with six different internal configurations. Overall, we tested 10 modified filter designs and compared them with the original commercial filter. Except for the combination of 1.5-μm filter paper and 5 mm sponge peak inspiratory pressure and circuit compliance of the filters produced were within the operating limits of the ventilator. All In addition, all filters passed the dye test.

conclusionsOur filter may be of particular importance to those working in low middle-income countries unable to compete with stronger economies. Our design relies on products available outside the healthcare supply chain, much of which can be purchased in grocery stores, hardware stores, or industrial and academic institutions. We hope that these HMEs and viral filters may be beneficial to clinicians who face critical supply chain issues during the COVID-19 pandemic.

Indexed as

Printing, Three-DimensionalVentilators, MechanicalVirusesColoring AgentsCOVID-19Equipment DesignFeasibility StudiesHumansPandemicsPaperPeak Expiratory Flow RatePolyurethanesReproducibility of ResultsSurgical SpongesUltrafiltrationColoring AgentsPolyurethanes3D printingAnesthesiaCOVID-19Global HealthVentilator

Identifiers

PMID33853526
PMCPMC8044501

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.