Evidence map›Paper›PMID 33853352›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Synaptotagmin-Like Protein 2a Regulates Angiogenic Lumen Formation via Weibel-Palade Body Apical Secretion of Angiopoietin-2.

Caitlin R Francis, Shea Claflin, Erich J Kushner

Open access · greenAbstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

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  10. Tip-end fusion of a rod-shaped secretory organelle.Cellular and molecular life sciences : CMLS · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Caitlin R FrancisDepartment of Biological Sciences, University of Denver, CO.
Shea ClaflinDepartment of Biological Sciences, University of Denver, CO.
Erich J KushnerDepartment of Biological Sciences, University of Denver, CO.
University of Denver · US

Funding

Centrosomes and Cytoskeletal Mechanisms of Blood Vessel DysfunctionR00HL124311 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KUSHNER, ERICH J · 2017 to 2019
$746k
Mechanisms of Basement Membrane Regulation During AngiogenesisR56HL148450 · NHLBI · UNIVERSITY OF DENVER (COLORADO SEMINARY) · PI KUSHNER, ERICH J · 2019 to 2019
$372k
Centrosomes and Cytoskeletal Mechanisms of Blood Vessel DysfunctionK99HL124311 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KUSHNER, ERICH J · 2015 to 2016
$238k
NHLBI NIH HHS K99 HL124311NHLBI NIH HHS R00 HL124311NHLBI NIH HHS R56 HL148450
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

ExocytosisNeovascularization, PhysiologicAngiopoietin-2AnimalsAnimals, Genetically ModifiedCells, CulturedHumansHuman Umbilical Vein Endothelial CellsMembrane Proteinsrab27 GTP-Binding ProteinsReceptor, TIE-2Signal TransductionWeibel-Palade BodiesZebrafishZebrafish ProteinsAngiopoietin-2ANGPT2 protein, humanMembrane ProteinsRAB27A protein, humanrab27 GTP-Binding ProteinsReceptor, TIE-2sytl2a protein, zebrafishSYTL2 protein, humanTEK protein, humantek protein, zebrafishZebrafish Proteinsangiopoietin-2cell membraneendothelial cellssecretory pathwaysynaptotagmins

Identifiers

PMID33853352
PMCPMC8159857
OpenAlexW3152850225

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.