Evidence map›Paper›PMID 33853350›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Clarifying the Distinct Roles of Smooth Muscle Cell-Derived Versus Macrophage Foam Cells and the Implications in Atherosclerosis.

Clint L Miller, Hanrui Zhang

Abstract readEditorialComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Clint L MillerDepartment of Public Health Sciences, Center for Public Health Genomics, University of Virginia, Charlottesville (C.L.M.).
Hanrui ZhangCardiometabolic Genomics Program, Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center, New York (H.Z.).

Funding

Multimodal genetic regulatory architecture of coronary artery diseaseR01HL148239 · NHLBI · UNIVERSITY OF VIRGINIA · PI Clint L Miller · 2019 to 2026
$4.2M
Discovering Wdfy3 as a novel regulator of macrophage efferocytosis by genome-wide CRISPR screenR01HL151611 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHANG, HANRUI · 2020 to 2024
$3.0M
EPISTATIC REGULATORY MECHANISMS OF CORONARY HEART DISEASE RISKR00HL125912 · NHLBI · UNIVERSITY OF VIRGINIA · PI MILLER, CLINT L · 2017 to 2019
$747k
Macrophage-specific function of GWAS CAD-associated LIPA alleles in atherosclerosisR00HL130574 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ZHANG, HANRUI · 2018 to 2020
$733k
Epistatic Regulatory Mechanisms of Coronary Heart Disease RiskK99HL125912 · NHLBI · STANFORD UNIVERSITY · PI MILLER, CLINT L · 2015 to 2016
$285k
NHLBI NIH HHS K99 HL125912NHLBI NIH HHS R00 HL125912NHLBI NIH HHS R00 HL130574NHLBI NIH HHS R01 HL148239NHLBI NIH HHS R01 HL151611
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AtherosclerosisFoam CellsHumansMacrophagesMyocytes, Smooth Muscleatherosclerosisblood vesselsEditorialsfoam cellslipidsmacrophagesmonocytesvascular

Identifiers

PMID33853350
PMCPMC8159896

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.