Evidence map›Paper›PMID 33853347›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Carbon Monoxide Suppresses Neointima Formation in Transplant Arteriosclerosis by Inhibiting Vascular Progenitor Cell Differentiation.

Hideyasu Sakihama, Ghee Rye Lee, Beek Y Chin, Eva Csizmadia, David Gallo, Yilin Qi, Nicola Gagliani, Hongjun Wang, Fritz H Bach, Leo E Otterbein

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 4 countries.

Hideyasu Sakihama *Department of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
Ghee Rye Lee *Department of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
Beek Y ChinInternational Medical University, Kuala Lumpur (B.Y.C.).
Eva CsizmadiaDepartment of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
David GalloDepartment of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
Yilin QiAgios Pharmaceuticals, Cambridge, MA (Y.Q.).
Nicola GaglianiDepartment of Medicine, University Medical Center Hamburg-Eppendorf, Germany (N.G.).
Hongjun WangDepartment of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
Fritz H BachDepartment of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
Leo E OtterbeinDepartment of Surgery, Harvard Medical School, Beth Israel Deaconess Medical Center, Boston, MA (H.S., G.R.L., E.C., D.G., H.W., F.H.B., L.E.O.).
Beth Israel Deaconess Medical Center · USAgios Pharmaceuticals (United States) · USHokkaido University of Science · JPIMU University · MYUniversität Hamburg · DE

Funding

Heme Oxygenase-1: protection against chronic rejectionR01HL077721 · NHLBI · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BACH, FRITZ H · 2006 to 2009
$1.7M
Carbon Monoxide to Prevent Circulatory CollapseR01HL076167 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI OTTERBEIN, LEO E · 2004 to 2007
$1.6M
NHLBI NIH HHS R01 HL076167NHLBI NIH HHS R01 HL077721
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

NeointimaAnimalsAorta, ThoracicArteriosclerosisBone Marrow TransplantationCarbon MonoxideCell DifferentiationCells, CulturedDisease Models, AnimalHeme Oxygenase-1KineticsMaleMembrane ProteinsMiceMice, Inbred BALB CMice, Inbred C57BLCarbon MonoxideHeme Oxygenase-1Hmox1 protein, mouseMembrane ProteinsReceptor, Platelet-Derived Growth Factor betabone marrowcarbon monoxideheme oxygenase-1neointimaplatelet-derived growth factor receptor

Identifiers

PMID33853347
PMCPMC8159904
OpenAlexW3152967155

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.