Evidence map›Paper›PMID 33852850›Full record

ArticleCell reports2021

Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes.

Deepyan Chatterjee, Fiona J Lewis, Henry J Sutton, Joe A Kaczmarski, Xin Gao, Yeping Cai, Hayley A McNamara, Colin J Jackson, Ian A Cockburn

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Protective near-germline antibodies to malaria elicited by RTS,S/AS01bioRxiv : the preprint server for biology · 2026
    Article
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  8. The N-terminal region of malaria vaccine candidatebioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. A Novel Gene Synthesis Platform for Designing Functional Protein Polymers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Deepyan ChatterjeeDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Fiona J LewisDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Henry J SuttonDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Joe A KaczmarskiResearch School of Chemistry, The Australian National University, Canberra, ACT 2601, Australia.
Xin GaoDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Yeping CaiDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Hayley A McNamaraDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia.
Colin J JacksonResearch School of Chemistry, The Australian National University, Canberra, ACT 2601, Australia.
Ian A CockburnDepartment of Immunology and Infectious Disease, John Curtin School of Medical Research, The Australian National University, Canberra, ACT 2601, Australia. Electronic address: ian.cockburn@anu.edu.au.
Australian National University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibodies targeting the NANP/NVDP repeat domain of the Plasmodium falciparum circumsporozoite protein (CSP

Indexed as

AnimalsAnophelesAntibodies, NeutralizingAntibodies, ProtozoanB-LymphocytesFemaleGene ExpressionImmunizationMalariaMalaria VaccinesMiceMice, Inbred C57BLPeptidesPlasmodium bergheiPlasmodium falciparumProtein BindingAntibodies, NeutralizingAntibodies, Protozoancircumsporozoite protein, ProtozoanMalaria VaccinesPeptidesProtozoan ProteinsVaccines, AttenuatedB cellscircumsporozoite proteinimmunodominanceimmunodominationmalariamalaria vaccinesPlasmodium falciparum

Identifiers

PMID33852850
PMCPMC8052187
OpenAlexW3155642526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.