Evidence map›Paper›PMID 33852722›Full record

ArticleAge and ageing2021

Acceptance and commitment therapy for late-life treatment-resistant generalised anxiety disorder: a feasibility study.

Rebecca L Gould, Julie Loebach Wetherell, Kate Kimona, Marc A Serfaty, Rebecca Jones, Christopher D Graham, Vanessa Lawrence, Gill Livingston, Philip Wilkinson, Kate Walters and 7 more

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Age and ageing, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 11 institutions in 4 countries.

Rebecca L GouldDivision of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
Julie Loebach WetherellMental Health Service, VA San Diego Healthcare System, San Diego, CA, USA.
Kate KimonaDivision of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
Marc A SerfatyDivision of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
Rebecca JonesDivision of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
Christopher D GrahamSchool of Psychology, Queen's University Belfast, Belfast, Northern Ireland.
Vanessa LawrenceHealth Services and Population Research Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Gill LivingstonDivision of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
Philip WilkinsonDepartment of Psychiatry, University of Oxford, Oxford, UK.
Kate WaltersDepartment of Primary Care and Population Health, University College London, London, UK.
Marie Le NovereDepartment of Primary Care and Population Health, University College London, London, UK.
Iracema LeroiGlobal Brain Health Institute, School of Medicine, Trinity College Dublin, Dublin, Ireland.
Robert BarberCentre for Health of the Elderly, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, UK.
Ellen LeeClinical Trials Research Unit, School of Health and Related Research, University of Sheffield, Sheffield, UK.
Jo CookThe Bexleyheath Centre, Oxleas NHS Foundation Trust, Bexleyheath, UK.
Viviana M WuthrichDepartment of Psychology, Centre for Emotional Health, Macquarie University, Sydney, Australia.
Robert J HowardDivision of Psychiatry, Faculty of Brain Sciences, University College London, London, UK.
University College London · GBFaculty (United Kingdom) · GBKing's College London · GBMacquarie University · AUNewcastle University · GBOxleas NHS Foundation Trust · GBQueen's University Belfast · GBTrinity College Dublin · IEUniversity of California, San Diego · USUniversity of Oxford · GBUniversity of Sheffield · GB

Funding

Department of Health 15/161/05
6 · The paper itself

Abstract

backgroundGeneralised anxiety disorder (GAD) is the most common anxiety disorder in older people. First-line management includes pharmacological and psychological therapies, but many do not find these effective or acceptable. Little is known about how to manage treatment-resistant generalised anxiety disorder (TR-GAD) in older people.

objectivesTo examine the acceptability, feasibility and preliminary estimates of the effectiveness of acceptance and commitment therapy (ACT) for older people with TR-GAD.

participantsPeople aged ≥65 years with TR-GAD (defined as not responding to GAD treatment, tolerate it or refused treatment) recruited from primary and secondary care services and the community.

interventionParticipants received up to 16 one-to-one sessions of ACT, developed specifically for older people with TR-GAD, in addition to usual care. MEASUREMENTS: Co-primary outcomes were feasibility (defined as recruitment of ≥32 participants and retention of ≥60% at follow-up) and acceptability (defined as participants attending ≥10 sessions and scoring ≥21/30 on the satisfaction with therapy subscale). Secondary outcomes included measures of anxiety, worry, depression and psychological flexibility (assessed at 0 and 20 weeks).

resultsThirty-seven participants were recruited, 30 (81%) were retained and 26 (70%) attended ≥10 sessions. A total of 18/30 (60%) participants scored ≥21/30 on the satisfaction with therapy subscale. There was preliminary evidence suggesting that ACT may improve anxiety, depression and psychological flexibility.

conclusionsThere was evidence of good feasibility and acceptability, although satisfaction with therapy scores suggested that further refinement of the intervention may be necessary. Results indicate that a larger-scale randomised controlled trial of ACT for TR-GAD is feasible and warranted.

Indexed as

Acceptance and Commitment TherapyCognitive Behavioral TherapyAgedAnxietyAnxiety DisordersFeasibility StudiesHumansacceptance and commitment therapyfeasibilitygeneralised anxiety disorderolder peopletreatment-resistant

Identifiers

PMID33852722
PMCPMC8437065
OpenAlexW3128999422

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.