ArticlePloS one2021
Pollen-food allergy syndrome and component sensitization in adolescents: A Japanese population-based study.
Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 37 citations in OpenAlex.
- Review
- [Pollen-food allergy syndrome: association between allergen cross-reactivity and symptom severity].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Article
- Oral symptoms suggestive of oral allergy syndrome in Japanese schoolchildren according to causative food families.Asia Pacific allergy · 2025Article
- Prevalence and sensitization of pollen-food allergy syndrome among adolescents in Tokyo.The journal of allergy and clinical immunology. Global · 2025Article
- Lung functions and IgE component sensitizations: Five wheezing phenotypes in adolescents from the T-Child study in Tokyo.The journal of allergy and clinical immunology. Global · 2025Article
- Prevalence and Associated Factors of Oral Allergy Syndrome among Mexican Adults: A Survey-Based Study: Oral Allergy Syndrome.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Exploring geographical variances in component-resolved diagnosis within the Asia-Pacific region.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025Review
- Prevalence and aeroallergen sensitization in pediatric Allergic Rhinitis: A population-based study in Jeju, Korea.PloS one · 2025Article
- Botanical Impurities in the Supply Chain: A New Allergenic Risk Exacerbated by Geopolitical Challenges.Nutrients · 2024Review
- Pollen Food Allergy Syndrome in Japanese Children and Adolescents: Risk Factors and Pollen Sensitisation.Journal of immunology research · 2023Article
- Real-life evaluation of molecular multiplex IgE test methods in the diagnosis of pollen associated food allergy.Allergy · 2022Article
- Safety evaluation of the food enzyme chymosin from the genetically modifiedEFSA journal. European Food Safety Authority · 2022Article
- Safety evaluation of the food enzyme chymosin from the genetically modifiedEFSA journal. European Food Safety Authority · 2022Article
- Safety evaluation of the food enzyme chymosin from the genetically modifiedEFSA journal. European Food Safety Authority · 2022Article
- Pollen Food Allergy Syndrome in Allergic March.Nutrients · 2022Article
- Japanese Cedar Pollen Allergens in Japan.Current protein & peptide science · 2022Article
- Surveillance of pollen-food allergy syndrome in elementary and junior high school children in Saitama, Japan.Asia Pacific allergy · 2022Article
Corrections and comments
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Authors and funding
16 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Allergic rhino-conjunctivitis with pollen allergy has been prevalent worldwide and Pollen-food allergy syndrome (PFAS) refers to individuals with pollen allergy who develop oral allergy syndrome (OAS) on consuming fruits and vegetables. The prevalence of PFAS varies by region and that in Japanese adolescents remains to be elucidated. In this cross-sectional study, we examined the epidemiological characteristics of PFAS in a general population of Japanese adolescents according to pollen allergy, OAS, and IgE component sensitization. Participants comprised adolescents, at age 13 years, from a prospective birth cohort study in Japan. We administered questionnaires to collect information from parents regarding pollen allergy, PFAS and OAS at each child's age 13 years. ImmunoCAP ISAC was used to assess IgE component sensitization. Among 506 participants with a complete questionnaire and ISAC measurement results, 56.5% had a history of hay fever, 16.0% had a history of OAS, 51.0% had pollen allergy, and 11.7% had a history of PFAS; additionally, 72.7% were sensitized to one or more tree, grass, and/or weed allergens. The most common sensitization (95.7%) among adolescents with pollen allergy was to Japanese cedar (Cry j 1). The most common causal foods were kiwi and pineapple (both 39.0%). Knowledge levels about PFAS were poor among affected adolescents. We found a high prevalence of PFAS among adolescents in Japan. Although it affects approximately 1/10 adolescents in the general population, public awareness regarding PFAS is poor. Interventional strategies are needed to increase knowledge and to prevent PFAS in the general population.
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