Evidence map›Paper›PMID 33852606›Full record

ArticlePloS one2021

Determination of reference intervals for knee motor functions specific to patients undergoing knee arthroplasty.

Hideyuki Ito, Kiyoshi Ichihara, Kotaro Tamari, Tetsuya Amano, Shigeharu Tanaka, Shigehiro Uchida, Shinya Morikawa

Open access · goldAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 4 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 7 institutions in 1 country.

Hideyuki ItoDepartment of Rehabilitation, Faculty of Wakayama Health Care Sciences, Takarazuka University of Medical and Health Care, Wakayama, Japan.
Kiyoshi IchiharaFaculty of Health Sciences, Yamaguchi University Graduate School of Medicine, Ube, Japan.ORCID 0000-0002-6039-4537
Kotaro TamariDepartment of Physical Therapy, Faculty of Health and Medical Science Teikyo Heisei University, Tokyo, Japan.
Tetsuya AmanoDepartment of Physical Therapy, Faculty of Health and Medical Sciences, Tokoha University, Hamamatsu, Japan.
Shigeharu TanakaDivision of Physical Therapy, School of Rehabilitation, Faculty of Health and Social Services, Kanagawa University of Human Services, Yokosuka, Japan.
Shigehiro UchidaDepartment of Rehabilitation, Faculty of Rehabilitation, Hiroshima International University, Higashihiroshima, Japan.
Shinya MorikawaDepartment of Rehabilitation, Hoshasen Daiichi Hospital, Imabari, Japan.
Daiyukai General Hospital · JPHiroshima International University · JPKanagawa University of Human Services · JPTakarazuka University of Medical and Health Care · JPTeikyo Heisei University · JPTokoha Gakuen University · JPYamaguchi University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients with knee osteoarthritis (KOA) undergoing knee arthroplasty (KA), lower-limb motor function tests are commonly measured during peri-surgical rehabilitation. To clarify their sources of variation and determine reference intervals (RIs), a multicenter study was performed in Japan.

methodsWe enrolled 545 KOA patients (127 men; 418 women; mean age 74.2 years) who underwent KA and followed a normal recovery course. The surgical modes included total KA (TKA), minimally invasive TKA (MIS-TKA), and unicompartmental KA (UKA). Motor functions measured twice before and two weeks after surgery included timed up-and-go (TUG), maximum walking speed (MWS), extensor and flexor muscle strength (MS), and knee range of motion (ROM). Multiple regression analysis was performed to evaluate their sources of variation including sex, age, BMI, and surgical mode. Magnitude of between-subgroup differences was expressed as SD ratio (SDR) based on 3-level nested ANOVA. SDR≥0.4 was set as the threshold for requiring RIs specific for each subgroup.

resultsBefore surgery, age-related changes exceeding the threshold were observed for TUG and MWS. Between-sex difference was noted for extensor and flexor MS, but extension and flexion ROMs were not influenced by sex or age. After surgery, in addition to similar influences of sex and age on test results, surgical modes of UKA and MIS-TKA generally had a favorable influence on MWS, extensor MS, and flexion ROM. All motor function test results showed a variable degree of skewness in distribution, and thus RIs were basically derived by the parametric method after Gaussian transformation of test results.

conclusionsThis is the first study to determine RIs for knee motor functions specific to KOA patients after careful consideration of their sources of variation and distribution shapes. These RIs facilitate objective implementation of peri-surgical rehabilitation and allow detection of patients who deviate from the normal course of recovery.

Indexed as

AgedAged, 80 and overAgingArthroplasty, Replacement, KneeCase-Control StudiesFemaleHumansJapanKnee JointMaleOsteoarthritis, KneeProspective StudiesRange of Motion, ArticularTreatment OutcomeWalking Speed

Identifiers

PMID33852606
PMCPMC8046200
OpenAlexW3153500826

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.