Evidence map›Paper›PMID 33852168›Full record

ArticleHuman psychopharmacology2021

Initiation of psychotropic medication in hospitalized patients with COVID-19: Association with clinical and biological characteristics.

Enrico Capuzzi, Alice Caldiroli, Silvia Leo, Massimiliano Buoli, Massimo Clerici

Open access · bronzeAbstract read
In one paragraph

Article in Human psychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Enrico CapuzziPsychiatric Department, Azienda Socio Sanitaria Territoriale Monza, Monza, Italy.ORCID 0000-0001-8350-499X
Alice CaldiroliPsychiatric Department, Azienda Socio Sanitaria Territoriale Monza, Monza, Italy.
Silvia LeoDepartment of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.
Massimiliano BuoliDepartment of Neurosciences and Mental Health, Fondazione IRCCS Ca'Granda Ospedale Maggiore Policlinico, Milan, Italy.
Massimo ClericiPsychiatric Department, Azienda Socio Sanitaria Territoriale Monza, Monza, Italy.
Azienda Socio Sanitaria Territoriale Lariana · ITUniversity of Milan · ITUniversity of Milano-Bicocca · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionInpatients with coronavirus disease 2019 (COVID-19) show a high rate of neuropsychiatric manifestations, possibly related to a higher risk of serious illness or death. Use of psychotropic medications (PMs) indicates the presence of neuropsychiatric symptoms in COVID-19 patients. So far, potential clinical predictors of use of PMs have not been much investigated. In order to extend research in this area, we aimed to investigate the prevalence of PM prescription among a sample of inpatients with COVID-19 and to find potential predictors of initiation of PMs in these individuals.

methodsThis is a cross-sectional single-center study, conducted during the first outbreak peak in a hospital of northern Italy. Information on socio-demographic characteristics, comorbidities, routine blood test, use of potential COVID-19 treatments, and length of stay were retrieved from medical records.

resultsData were available for 151 inpatients. Forty-seven of them (31.1%) started at least one prescription of a PM. PM prescription was significantly inversely associated with lymphocyte and platelet counts. A significant association was also found for lactate dehydrogenase (LDH).

conclusionOur findings suggest that the initiation of PMs could be common among COVID-19 inpatients. Lymphocyte and platelet counts as well as LDH levels may reflect neuropsychiatric complications of COVID-19.

Indexed as

COVID-19 Drug TreatmentAgedAged, 80 and overCOVID-19Cross-Sectional StudiesFemaleHospitalizationHumansItalyMaleMental DisordersMiddle AgedPsychotropic DrugsPsychotropic DrugsCOVID-19inpatientneuropsychiatric symptomsprescriptionpsychotropic medication

Identifiers

PMID33852168
PMCPMC8250257
OpenAlexW3153271943

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.