Evidence map›Paper›PMID 33852058›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Pediatric anti-NMDA receptor encephalitis associated with COVID-19.

Esra Sarigecili, Ilknur Arslan, Habibe Koc Ucar, Umit Celik

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 7 pooled it
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 7 syntheses or guidelines pooled it, 60 citations in OpenAlex.

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  5. Immune-mediated neurological syndrome in SARS-CoV-2 infection: a review of literature on autoimmune encephalitis in COVID-19.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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  12. Case report: AntiFrontiers in psychiatry · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Esra SarigeciliDepartment of Pediatric Neurology, Adana City Training and Research Hospital, Adana, Turkey. sarigeciliesra@gmail.com.ORCID 0000-0001-8630-4950
Ilknur ArslanDepartment of Pediatric Intensive Care Unit, Adana City Training and Research Hospital, Adana, Turkey.ORCID 0000-0002-3454-8483
Habibe Koc UcarDepartment of Pediatric Neurology, Adana City Training and Research Hospital, Adana, Turkey.ORCID 0000-0001-8224-7725
Umit CelikDepartment of Pediatric Infectious Diseases, Adana City Training and Research Hospital, Adana, Turkey.ORCID 0000-0002-1200-0142

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-N-methyl-D-aspartate receptor encephalitis is a clinical condition characterized by acute behavioral and mood changes, abnormal movements, autonomic instability, seizures, and encephalopathy. We describe a 7-year-old boy diagnosed with autoimmune encephalitis due to NMDAR antibody in association with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019) (COVID-19), without pulmonary involvement or fever. The patient presented with acute ataxia, rapidly developed encephalopathy, and autoimmune encephalitis was suspected. Steroid treatment was withheld because of lymphopenia and intravenous immunoglobulin was started. The absence of clinical response prompted plasmapheresis and, when lymphocyte counts improved, pulse steroid treatment was applied. The latter was followed by significant improvement and the patient was discharged in a conscious and ambulatory state. Autoimmune encephalitis should be considered in the presence of neurological symptoms accompanying SARS-CoV-2 infection and steroid treatment should be preferred unless limited by contraindications.

Indexed as

Anti-N-Methyl-D-Aspartate Receptor EncephalitisCOVID-19ChildHumansImmunoglobulins, IntravenousMaleSARS-CoV-2SeizuresImmunoglobulins, IntravenousAnti-NMDA receptor encephalitisAtaxiaCOVID-19Pediatric

Identifiers

PMID33852058
PMCPMC8045445
OpenAlexW3153538687

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.