Evidence map›Paper›PMID 33852051›Full record

Trial reportEuropean journal of nuclear medicine and molecular imaging2021

Patterns of disease detection using [

Samantha Koschel, Kim Taubman, Thomas Sutherland, Kelvin Yap, Michael Chao, Mario Guerrieri, Angela Benson, Michelle Starmans, Graeme Byrne, Grace Ong and 5 more

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. The Diagnostic Role ofFrontiers in oncology · 2021
    Pooled it
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Changes in Management AfterJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2022
    Article
  10. Pathological predictors ofBJU international · 2022
    Article
  11. Piflufolastat F 18: Diagnostic First Approval.Molecular diagnosis & therapy · 2021
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Samantha KoschelGenesisCare Cancer Care Research, Melbourne, Australia.ORCID 0000-0002-0134-7423
Kim TaubmanDepartment of Nuclear Medicine, St Vincent's Hospital Melbourne, Melbourne, Australia.ORCID 0000-0001-9294-7530
Thomas SutherlandDepartment of Medical Imaging, St Vincent's Hospital Melbourne, Melbourne, Australia.ORCID 0000-0001-9668-1995
Kelvin YapDepartment of Medical Imaging, St Vincent's Hospital Melbourne, Melbourne, Australia.
Michael ChaoGenesisCare, Ringwood, Australia.
Mario GuerrieriGenesisCare, Footscray, Australia.
Angela BensonGenesisCare Cancer Care Research, Melbourne, Australia.
Michelle StarmansGenesisCare Cancer Care Research, Melbourne, Australia.
Graeme ByrneLa Trobe University Statistics Consultancy Platform, Melbourne, Australia.
Grace OngGenesisCare, Shepparton, Australia.
Craig MacleodGenesisCare, Albury, Australia.
Marcus FooGenesisCare, Berwick, Australia.
Lih Ming WongDepartment of Surgery, University of Melbourne, Melbourne, Australia.ORCID 0000-0003-0490-7876
Dennis GyomberDepartment of Urology, Northern Hospital, Epping, Australia.ORCID 0000-0001-6735-5170
Michael NgGenesisCare, St Vincent's Hospital, Melbourne, Australia. michael.ng@genesiscare.com.ORCID 0000-0003-3539-9237

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeProstate-specific membrane antigen (PSMA) PET/CT is increasingly used in patients with biochemical recurrence post prostatectomy to detect local recurrence and metastatic disease at low PSA levels. The aim of this study was to assess patterns of disease detection, predictive factors and safety using [

methodsWe conducted a prospective trial recruiting 100 patients with detectable PSA post prostatectomy (PSA 0.2-2.0 ng/mL) and referred for salvage radiotherapy from August 2018 to July 2020. All patients underwent a PSMA PET/CT using the [

resultsOf 100 patients recruited, 98 were suitable for analysis with a median PSA of 0.32 ng/mL. [

conclusions[

trial registrationAustralian New Zealand Clinical Trials Registry Number: ACTRN12618001530213 ( http://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=375932&isReview=true ).

Indexed as

Positron Emission Tomography Computed TomographyProstatic NeoplasmsAustraliaHumansMaleNeoplasm Recurrence, LocalProspective StudiesProstatectomyProstate-Specific AntigenProstate-Specific Antigen[18F]DCFPyLBiochemical recurrenceProstate cancerPSMA PETRadiotherapy

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.